TUBA3C antibody (N-Term)

Catalog No. ABIN311613

Product Details anti-TUBA3C Antibody

Target: TUBA3C (Tubulin, Alpha, 3C (TUBA3C))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBA3C antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VDLEPTVVDE VRTGTYRQLF HPEQLITGKE DAANNYARGH YTIGKEIVDL

Predicted Reactivity: Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TUBA3C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TUBA3C

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 450 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TUBA3C

Target: TUBA3C (Tubulin, Alpha, 3C (TUBA3C))

Alternative Name: TUBA3C (TUBA3C Products)

Synonyms: TUBA2 antibody, bA408E5.3 antibody, TUBA1A antibody, TUBA3 antibody, TUBA3C antibody, TUBA3D antibody, 3t antibody, ALPHA 84D antibody, CG2512 antibody, D.m.ALPHA-84D antibody, DTA4 antibody, Dmel\CG2512 antibody, T antibody, Tub antibody, Tub1A antibody, aTub84D antibody, alpha-Tub antibody, alpha-Tub84D antibody, alpha-tub antibody, alpha-tub84D antibody, alpha-tubulin antibody, alpha3 antibody, alpha3t antibody, alpha84D antibody, alphaTUB antibody, alphaTUB84D antibody, alphaTub antibody, alphaTub3 antibody, alphaTub84 antibody, tuba2 antibody, tuba3c antibody, tuba3d antibody, GRMZM2G153292 antibody, TUA2 antibody, zgc:73108 antibody, tubulin alpha 3c antibody, tubulin, alpha 3A antibody, tubulin alpha like 3 antibody, tubulin alpha-1B chain antibody, tubulin alpha-1A chain antibody, alpha-Tubulin at 84D antibody, tubulin alpha 3c S homeolog antibody, tubulin alpha-2 chain-like antibody, tubulin, alpha 2 antibody, TUBA3C antibody, Tuba3a antibody, TUBAL3 antibody, LOC610636 antibody, LOC782966 antibody, alphaTub84D antibody, tuba3c.S antibody, LOC103643947 antibody, tuba2 antibody

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99 % identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome.Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99 % identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TUBA2, bA408E5.3, TUBA3D
Protein Interaction Partner: CEP70, UBC, MDM2, CD81, K3, UBL4A, DYNLT1, TSGA10, CUL3, ARRB2, ARRB1, VHL, YWHAQ, DYRK2, YWHAZ, YWHAG, YWHAB, PPP4C, PFDN5, GRM7, NMI, PXN, SIAH1, DYNLL1, TUBG1, MYC, FYN, FBL,
Protein Size: 450

Molecular Weight: 50 kDa

Gene ID: 7278

NCBI Accession: NM_006001, NP_005992

UniProt: Q13748

Pathways: Microtubule Dynamics