Ubiquilin 3 antibody (N-Term)

Catalog No. ABIN311631

Product Details anti-Ubiquilin 3 Antibody

Target: Ubiquilin 3 (UBQLN3)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Pig, Rabbit, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubiquilin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LMRQHVSVPE FVTQLIDDPF IPGLLSNTGL VRQLVLDNPH MQQLIQHNPE

Predicted Reactivity: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against UBQLN3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBQLN3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 655 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Ubiquilin 3

Target: Ubiquilin 3 (UBQLN3)

Alternative Name: UBQLN3 (UBQLN3 Products)

Synonyms: TUP-1 antibody, 4933400K24Rik antibody, UBQLN3 antibody, ubiquilin 3 antibody, UBQLN3 antibody, Ubqln3 antibody

Background: UBQLN3 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. UBQLN3 is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis. This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis.
Alias Symbols: TUP-1
Protein Size: 655

Molecular Weight: 72 kDa

Gene ID: 50613

NCBI Accession: NM_017481, NP_059509

UniProt: Q9H347