CD20 (cytoplasmic) antibody
| Antigen |
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Epitope
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cytoplasmic
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| Clonality |
Monoclonal (1412) |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN311768 |
| Quantity |
100 tests (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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CD20 (cytoplasmic)
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Isotype
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IgG2a, kappa chain (Matching secondary antibodies)
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Clone
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1412
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Description
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CD20 is a 33-37 kD four transmembrane spanning protein also known as B1 and Bp35. CD20 is expressed onpre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cellsubset. CD20 is heavily phosphorylated in activated B cells and malignant B cells. Homo-oligomeric complexes ofCD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule isinvolved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn), and exists in a complexwith MHC class I and II, CD53, CD81, and CD82. The mAb 1412 recognizes the cytoplasmic domain of the CD20molecule.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor
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Purification
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The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor 488 under optimalconditions. The solution is free of unconjugated Alexa Fluor 488.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
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Storage
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do notfreeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "CD20", type "Antibodies"
Alternatives 
