CD160 Molecule (CD160) antibody (Alexa Fluor 647)

Antigen: CD160 Molecule (CD160)

Synonyms: NK1, BY55, NK28, FLJ46513, By55, AU045688, CD160, RGD1563598

Clonality: Monoclonal (BY55)

Host: Mouse

Reactivity: Human

Conjugate: Alexa Fluor 647

Application: Flow Cytometry (FACS)

Catalog no.: ABIN311820

Additional Information

Alternative name: CD160

Isotype: IgM, kappa chain

Clone: BY55

Description: CD160 is a 27 kD GPI-anchored glycoprotein, also known as BY55, NK1, and NK28. A member the Ig superfamily, CD160 exists as a disulfide-bond multimer, expressed on the surface of a subpopulation of NK cells, gamma/delta T cells,subset of CD8+ T cells, and intestinal intraepithelial lymphocytes (IEL). CD160 plays costimulatory roles throughbinding to classical and nonclassical MHC-I molecules.

Application Details

Application Notes: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor 647 under optimalconditions. The solution is free of unconjugated Alexa Fluor 647.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Storage: The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do notfreeze.

Restrictions: For Research Use only

Publications

Publications: Mauiza, Leca, Mansur et al.: "A novel 80-kD cell surface structure identifies human circulating lymphocytes with natural killer activity." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 1121-6, 1993 (PubMed).

Anumanthan, Bensussan, Boumsell et al.: "Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 6, pp. 2780-90, 1998 (PubMed).