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Antibodies
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anti-CD1c Molecule (CD1C) antibody (Alexa Fluor 647)
CD1c Molecule (CD1C) antibody (Alexa Fluor 647)
| Antigen |
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| Synonyms |
R7, CD1, CD1A, BDCA1, CD1C |
| Clonality |
Monoclonal (L161) |
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Host
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Reactivity
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Conjugate
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Alexa Fluor 647
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Application
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| Catalog no. |
ABIN311838 |
| Quantity |
100 tests (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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CD1c
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Isotype
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IgG1, kappa chain
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Clone
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L161
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Description
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CD1c, known as R7 or M241, is a 43 kD member of the five CD1 antigens (CD1a-e) in human. The CD1 moleculesare type I glycoprotein with the structural similarities to MHC class I and is non-covalently associated with beta2-microglobulin, belong to Ig superfamily. CD1c is expressed on cortical thymocytes, Langerhans cells, dendritic cells,and a subset of B cells. It has been reported that CD1c is also expressed on mature T cells with tightly regulatedmanner. The function of CD1c is involved in antigen-presentation of glycolipids. It may also act in T cells as animmune regulatory molecule.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor
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Purification
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The antibody was purified by affinity chromatography, and conjugated withAlexa Fluor 647 under optimal conditions. The solution is free of unconjugated Alexa Fluor 647.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
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Storage
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "CD1c Molecule (CD1C)", type "Antibodies"
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