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Antibodies
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anti-CD209 Molecule (CD209) antibody (Alexa Fluor 647)
CD209 Molecule (CD209) antibody (Alexa Fluor 647)
| Antigen |
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| Synonyms |
CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1, MGC129965, cd209, CD209, CLEC4M, si:ch211-224h1.3, CIRE, Dcsign, SIGNR5, SIGN-R1, MGC130443 |
| Clonality |
Monoclonal (9E9A8) |
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Host
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Reactivity
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Conjugate
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Application
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Flow Cytometry (FACS) (43), Western Blotting (WB) (29), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (12), Immunofluorescence (IF) (7), Immunoprecipitation (IP) (7), Functional Studies (Func) (4), ELISA (Detection) (3), Enzyme Immunoassay (EIA) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunohistochemistry (IHC) (2), ELISA (1)
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| Catalog no. |
ABIN311841 |
| Quantity |
25 tests (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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CD209 (DC-SIGN)
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Immunogen
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Extracellular domain of human DC-SIGN
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Isotype
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IgG2a, kappa chain
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Clone
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9E9A8
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Description
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CD209, known as Dendritic Cell-Specific Intercellular adhesion molecule 3 (ICAM-3)-Grabbing Nonintegrin(DC-SIGN), is a 44 kD type II transmembrane glycoprotein and a member of the C-type lectin family. CD209 isexpressed on myeloid dendritic cells, placental macrophages, liver and placental endothelial cells. CD209 binds toICAM-3 (CD50), ICAM-2 (CD102), and Butyrophilin (BTN2A1), and mediates dendritic cell migration and T cellproliferation. Importantly, CD209 is a receptor of HIV-1 and some other viruses (such as West Nile virus, hepatitis Cvirus, etc), and some bacteria or parasites. It plays a criti-cal role in capturing and internalizing those pathogens.LSP1 (leukocyte-specific protein 1) interacts with the cytoplasmic domain of CD209 and mediates transport of HIV tothe proteasome.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor
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Purification
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The antibody was purified by affinity chromatography, and conjugated withAlexa Fluor 647 under optimal conditions. The solution is free of unconjugated Alexa Fluor 647.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
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Storage
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "CD209 Molecule (CD209)", type "Antibodies"
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Hosts
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Mouse (30), Rat (26), Rabbit (16)
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Reactivities
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Human (54), Mouse (Murine) (16), Monkey (1)
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Applications
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Flow Cytometry (FACS) (43), Western Blotting (WB) (29), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (12), Immunofluorescence (IF) (7), Immunoprecipitation (IP) (7), Functional Studies (Func) (4), ELISA (Detection) (3), Enzyme Immunoassay (EIA) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunohistochemistry (IHC) (2), ELISA (1)
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Conjugates
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Biotin (10), PE (9), FITC (8), APC (3), Cy5.5 (2), RPE (2)
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Epitopes
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AA 277-293 (2), AA 210-395 (1), AA 384-404 (1), extracellular domain (1)
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Alternatives 
