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Antibodies
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) antibody (...
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) antibody (Alexa Fluor 647)
| Antigen |
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| Synonyms |
BAFFR, CD268, BAFF-R, MGC138235, RGD1560810, TNFRSF13C |
| Clonality |
Monoclonal (11C1) |
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Host
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Reactivity
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Conjugate
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Alexa Fluor 647
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Application
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| Catalog no. |
ABIN311843 |
| Quantity |
100 tests |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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CD268 (BAFF-R, BAFFR)
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Immunogen
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BAFF-R-L1.2 transfectants
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Isotype
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IgG1, kappa chain
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Clone
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11C1
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Description
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B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, alsoknown as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on matureB cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) whichbinds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-kappa B activation and playspredominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-kappa B activation.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor
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Purification
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The antibody was purified by affinity chromatography, and conjugated withAlexa Fluor 647 under optimal conditions. The solution is free of unconjugated Alexa Fluor 647 and unconjugated antibody.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
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Storage
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C)", type "Antibodies"
Alternatives 
