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Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily Member 8 TNFRSF8 Alexa Fluor 647
Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibody (Alexa Fluor 647)
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| Synonyms |
CD30, Ki-1, D1S166E |
| Clonality |
Monoclonal (BY88) |
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Host
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Reactivity
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Conjugate
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Application
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| Catalog no. |
ABIN311848 |
| Quantity |
25 tests (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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CD30
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Immunogen
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Recombinant human CD30 boosted with THP-1 cell line
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Isotype
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IgG1, kappa
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Clone
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BY88
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Description
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CD30, also known as Ki-1 antigen, lymphoid activation antigen CD30, and tumor necrosis factor receptor superfamilymember 8 is a type I transmembrane receptor that contains four TNF receptor domains with an approximatemolecular weight of 64 kD. CD30 is highly expressed on Hodgkins and Reed-Sternberg cells as well as activated, butnot resting, T and B cells. CD30 has been shown to interact with a number of proteins including TRAF1, TRAF2,TRAF3, TRAF5, NPM-ALK, TRAF-interacting protein, and CD30 ligand (CD153). Signaling through CD30 is thoughtto limit the proliferative potential of autoreactive CD8 effector T cells and protect against autoimmunity.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor
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Purification
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The antibody was purified by affinity chromatography, and conjugated withAlexa Fluor 647 under optimal conditions. The solution is free of unconjugated Alexa Fluor 647 and unconjugated antibody.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
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Storage
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8)", type "Antibodies"
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Hosts
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Mouse (45), Hamster (19), Rat (16), Rabbit (7)
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Reactivities
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Human (48), Mouse (Murine) (36), Monkey (3)
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Applications
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Flow Cytometry (FACS) (56), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (25), Enzyme Immunoassay (EIA) (9), Immunohistochemistry (Frozen Sections) (IHC (fro)) (9), Western Blotting (WB) (9), ELISA (5), Immunoprecipitation (IP) (5), Functional Studies (Func) (3), Blocking Antibody (Inhibition) (2), Immunofluorescence (IF) (1)
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Conjugates
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FITC (12), PE (12), Biotin (4), APC (2), RPE (1)
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Alternatives 
