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Frizzled Family Receptor 9 antibody (Alexa Fluor 647)

Antigen

Frizzled Family Receptor 9

Synonyms FZD3, CD349, mfz9
Clonality Monoclonal (W3C4E11)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Conjugate
Alexa Fluor 647
Application
Alternatives Flow Cytometry (FACS)
Catalog no. ABIN311856
Quantity 25 tests  (Variants)
Price Product not available in this region.
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Additional Information

Alternative name CD349 (Frizzled-9)
Immunogen WERI-RB-1 retinoblastoma cells
Isotype IgM, kappa chain
Clone W3C4E11
Description CD349 is a member of the Frizzled family, known as Frizzled-9 (Fz9, FZD9, hFz9, or FzE6) which was originallydescribed as FZD3. Ten frizzled member have been identified in humans. FZD9 is a seven transmembraneG-protein-coupled receptor (GPCR), a receptor for Wnt proteins. It is involved in the activation of Wnt/beta-cateninpathway (canonic Wnt signaling). FZD9 is predominately expressed in fetal and adult brain, testis, eye, skeletalmuscle and kidney and is also expressed on Mesenchymal stem cells, and neural precursor cells. Frizzled proteinsplay important roles in controlling cell fate, proliferation, migration, tissue architecture and organogenesis duringembryonic development and in adult organisms. FZD9 is an important factor for nervous system development and iscritical for hippocampal development.

Application Details

Application Notes Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor
Purification The antibody was conjugated with Alexa Fluor 647 under optimalconditions, and is at >85% purity. The solution is free of unconjugated AlexaFluor 647.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
Storage The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Frizzled Family Receptor 9", type "Antibodies"
Hosts Rabbit (8), Goat (4)
Reactivities Human (8), Mouse (Murine) (5), Rat (Rattus) (3)
Applications Western Blotting (WB) (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Enzyme Immunoassay (EIA) (3), ELISA (2), Immunofluorescence (IF) (2), Immunohistochemistry (IHC) (1)
Epitopes N-Term (3)