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CD52 Molecule (CD52) antibody (Alexa Fluor 647)

Antigen

CD52 Molecule (CD52)

Synonyms CDW52, B7, MB7, CLS1, B7-Ag, AI463198, CAMPATH-1, CD52
Clonality Polyclonal
Host
Reactivity
Alternatives

Human

Conjugate
Alternatives Alexa Fluor 647
Application
Alternatives Flow Cytometry (FACS)
Catalog no. ABIN311862
Quantity 25 tests
Price Product not available in this region.
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Additional Information

Alternative name CD52
Isotype IgM, kappa
Clone 097
Description CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a largeN-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductivetract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells.CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target forcomplement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target forchronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression.

Application Details

Application Notes Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor
Purification The antibody was conjugated with Alexa Fluor 647 under optimalconditions, and is at >85% purity. The solution is free of unconjugated AlexaFluor 647.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
Storage The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
Restrictions For Research Use only