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Antibody
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anti-CD52 Molecule CD52 Alexa Fluor 647
CD52 Molecule (CD52) antibody (Alexa Fluor 647)
| Antigen |
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| Synonyms |
CDW52, B7, MB7, CLS1, B7-Ag, AI463198, CAMPATH-1, CD52 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Conjugate
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Application
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Flow Cytometry (FACS) (44), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (17), Immunohistochemistry (Frozen Sections) (IHC (fro)) (9), Cytotoxicity Test (CyTox) (7), Western Blotting (WB) (7), Immunoprecipitation (IP) (5), ELISA (3), Enzyme Immunoassay (EIA) (2), Immunohistochemistry (IHC) (2), Immunofluorescence (IF) (1), Immunohistochemistry (Resin Sections) (IHC (rs)) (1)
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| Catalog no. |
ABIN311862 |
| Quantity |
25 tests |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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CD52
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Isotype
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IgM, kappa
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Clone
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097
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Description
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CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a largeN-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductivetract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells.CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target forcomplement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target forchronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor
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Purification
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The antibody was conjugated with Alexa Fluor 647 under optimalconditions, and is at >85% purity. The solution is free of unconjugated AlexaFluor 647.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
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Storage
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "CD52 Molecule (CD52)", type "Antibodies"
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Hosts
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Mouse (34), Rat (13)
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Reactivities
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Human (47), Monkey (5), Rhesus Monkey (1)
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Applications
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Flow Cytometry (FACS) (44), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (17), Immunohistochemistry (Frozen Sections) (IHC (fro)) (9), Cytotoxicity Test (CyTox) (7), Western Blotting (WB) (7), Immunoprecipitation (IP) (5), ELISA (3), Enzyme Immunoassay (EIA) (2), Immunohistochemistry (IHC) (2), Immunofluorescence (IF) (1), Immunohistochemistry (Resin Sections) (IHC (rs)) (1)
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Conjugates
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FITC (9), APC (3), PE (3), RPE (3), Alexa Fluor 488 (1), Alexa Fluor 700 (1), Cy5 (1), Pacific Blue (1)
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