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Intercellular Adhesion Molecule 1 (ICAM1) antibody (Alexa Fluor 647)

Antigen

Intercellular Adhesion Molecule 1 (ICAM1)

Synonyms BB2, CD54, P3.58, Ly-47, Icam-1, MALA-2, MGC6195, ICAM-1, ICAM1, ICAM
Clonality Monoclonal (HCD54)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Conjugate
Alternatives Alexa Fluor 647
Application
Alternatives Flow Cytometry (FACS)
Catalog no. ABIN311864
Quantity 100 tests
Price Product not available in this region.
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Additional Information

Alternative name CD54
Isotype IgG1, kappa chain
Clone HCD54
Description CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelialcells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. Theexpression of ICAM-1 on the cell surface is potently upregulated by activation, a soluble form of ICAM-1 can bereleased from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyteextravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds toCD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen.

Application Details

Application Notes Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul ofwhole blood. It is recommended that the reagent be titrated for optimalperformance for each application.* Alexa Fluor
Purification The antibody was purified by affinity chromatography, and conjugated withAlexa Fluor 647 under optimal conditions. The solution is free of unconjugated Alexa Fluor 647.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
Storage The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Intercellular Adhesion Molecule 1 (ICAM1)", type "Antibodies"
Hosts Mouse (190), Rabbit (182), Rat (53), Hamster (4), Sheep (1)
Reactivities Human (339), Mouse (Murine) (141), Rat (Rattus) (97), Cow (Bovine) (56), Pig (Porcine) (44), Rabbit (43), Dog (Canine) (38), Sheep (Ovine) (18), Horse (Equine) (16), Chicken (4), Guinea Pig (2), Fish (1)
Applications Flow Cytometry (FACS) (328), Immunofluorescence (IF) (135), Western Blotting (WB) (126), Immunoprecipitation (IP) (81), Immunohistochemistry (Frozen Sections) (IHC (fro)) (76), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (62), ELISA (61), Immunohistochemistry (IHC) (20), Functional Studies (Func) (19), Enzyme Immunoassay (EIA) (14), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (12), Immunocytochemistry (ICC) (11), Blocking Antibody (Inhibition) (10), Immunoelectron Microscopy (IEM) (7), Blocking Antibody (Inhibition) (6), Immunohistochemistry (Fixed) (IHC (fx)) (5), ELISA (Detection) (2)
Conjugates Biotin (42), FITC (38), PE (29), Alexa Fluor 488 (8), Alexa Fluor 350 (7), Alexa Fluor 555 (7), Alexa Fluor 647 (7), Cy3 (7), Cy5 (7), Cy5.5 (7), Cy7 (7), Gold (7), HRP (7), PE,Cy3 (7), PE,Cy5 (7), PE,Cy5.5 (7), PE,Cy7 (7), RBITC (7), RPE (7), APC (6), Alexa Flour 488 (6), Alexa Fluor 700 (1), Pacific Blue (1), PerCP (1)
Epitopes pTyr512 (9), C-Term (2), AA 253-267 (1), Domain D1 (1)