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Integrin beta 3 (ITGB3) antibody (Alexa Fluor 647)
| Antigen | Integrin beta 3 (ITGB3) |
| Synonyms | LAD, CD18, MF17, MFI7, LCAMB, LFA-1, MAC-1, CD61, GP3A, GPIIIa, INGRB3, MGC159221, MGC159223, integrin, ITGB3 |
| Clonality | Monoclonal (VI-PL2) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Conjugate |
Alternatives Alexa Fluor 647 |
| Application |
Alternatives Flow Cytometry (FACS)
|
| Catalog no. | ABIN311867 |
| Quantity | 25 tests (Variants) |
| Price | Product not available in this region. |
| Shipping to |
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Additional Information
| Alternative name | CD61 |
| Isotype | IgG1, kappa chain |
| Clone | VI-PL2 |
| Description | Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal", mso-tstyle-rowband-size:0, mso-tstyle-colband-size:0,mso-style-noshow:yes, mso-style-priority:99, mso-style-qformat:yes, mso-style-parent:"", mso-padding-alt:0in 5.4pt0in 5.4pt, mso-para-margin:0in, mso-para-margin-bottom:.0001pt, mso-pagination:widow-orphan, font-size:11.0pt,font-family:"Calibri","sans-serif", mso-ascii-font-family:Calibri, mso-ascii-theme-font:minor-latin,mso-fareast-font-family:"Times New Roman", mso-fareast-theme-font:minor-fareast, mso-hansi-font-family:Calibri,mso-hansi-theme-font:minor-latin, mso-bidi-font-family:"Times New Roman", mso-bidi-theme-font:minor-bidi,} CD61, known as integrin b3 or glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is amember of integrin family that associates with platelet gpIIb (CD41) forming CD41/CD61 complex and associates withintegrin aV (CD51) forming aV/b3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes,and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF and otherRGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblast, macrophagesand some tumor cells, involved in tumor metastasis and in adenovirus infection through binding to RGD motif ECMproteins. |
Application Details
| Application Notes | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells in 100 ul volume or 5 ul per 100ul of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor |
| Purification | The antibody was purified by affinity chromatography, and conjugated withAlexa Fluor 647 under optimal conditions. The solution is free of unconjugated Alexa Fluor 647. |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA). |
| Storage | The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Integrin beta 3 (ITGB3)", type "Antibodies"
| Hosts | Mouse (55), Rabbit (47), Hamster (15) |
| Reactivities | Human (97), Mouse (Murine) (53), Rat (Rattus) (19), Monkey (10), Pig (Porcine) (4), Cow (Bovine) (2), Dog (Canine) (2), Horse (Equine) (2), Hamster (1) |
| Applications | Flow Cytometry (FACS) (56), Western Blotting (WB) (54), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (21), Immunohistochemistry (IHC) (19), Immunohistochemistry (Frozen Sections) (IHC (fro)) (15), Immunoprecipitation (IP) (12), ELISA (5), Enzyme Immunoassay (EIA) (3), Functional Studies (Func) (1) |
| Conjugates | FITC (18), PE (8), Biotin (7), RPE (3), APC (1) |
| Epitopes | pTyr773 (9), pTyr785 (8), Ab-773 (5), Ab-785 (5), N-Term (1) |
