Fc Receptor-Like A (FCRLA) antibody (Alexa Fluor 647)

Antigen: Fc Receptor-Like A (FCRLA)

Synonyms: FCRL, FCRX, FREB, FCRL1, FCRLX, FCRLb, FCRLd, FCRLe, FCRLM1, FCRLc1, FCRLc2, MGC4595, RP11-474I16.5, Fcrlm1, RGD1306176

Clonality: Polyclonal

Host: Please enquire

Reactivity: Human

Conjugate: Alexa Fluor 647

Application: Flow Cytometry (FACS)

Catalog no.: ABIN311883

Additional Information

Alternative name: FcRLA (FREB, FcRX)

Immunogen: Recombinant human FREB

Isotype: IgG1, kappa chain

Clone: N28-1

Description: Fc receptor-like A protein, also known as FCRL, FcRLA, FcRX, and FREB, is a cytoplasmic protein exhibiting twoIg-like C2-type and one C terminal mucin-like domains. Located on chromosome 1q23 the full length isoform is38kDa, though multiple splice variants have been reported. FcRLA is normally expressed in B-cells associated withtonsillar and splenic germinal centers and the splenic marginal zone. However, the immunogenicity of FcRLA inmultiple melanoma patients coupled with the variable expression reported in B-cell and Burkitt',s lymphomahighlight the role FcRLA may play in neoplasticity.

Application Details

Application Notes: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor

Purification: The antibody was conjugated with Alexa Fluor 647 under optimal conditions, and is at >85% purity. The solution is free of unconjugated Alexa Fluor 647.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Storage: The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do notfreeze.

Restrictions: For Research Use only