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Antibodies
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anti-IL-21 antibody (Alexa Fluor 647)
IL-21 antibody (Alexa Fluor 647)
| Antigen |
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| Clonality |
Monoclonal (3A3-N2) |
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Host
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Reactivity
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Conjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Application
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| Catalog no. |
ABIN311895 |
| Quantity |
25 tests (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Immunogen
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Recombinant full length human IL-21
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Isotype
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IgG1, kappa chain
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Clone
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3A3-N2
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Description
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Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularlythe inflammatory Th17 subset and has pleiotropic effects on both innate and adaptive immune responses. Theseactions include positive effects such as enhanced proliferation of natural killer (NK) cells and cytotoxic T cells that candestroy virally infected or cancerous cells and direct inhibitory effects on the antigen-presenting function of dendriticcells and can be proapoptotic for B cells and NK cells. Recent studies have shown that IL-21 is also an autocrinecytokine that potently induces T(H)17 differentiation and suppresses Foxp3 expression, and serves as a target fortreating inflammatory diseases.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor
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Purification
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The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor 647 under optimalconditions. The solution is free of unconjugated Alexa Fluor 647.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
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Storage
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do notfreeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "IL-21", type "Antibodies"
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Hosts
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Rabbit (21)
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Reactivities
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Human (21), Mouse (Murine) (20), Rat (Rattus) (20), Cow (Bovine) (17), Pig (Porcine) (17), Dog (Canine) (16), Horse (Equine) (2), Cat (Feline) (1), Rabbit (1), Sheep (Ovine) (1)
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Applications
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Flow Cytometry (FACS) (18), Immunofluorescence (IF) (18), Western Blotting (WB) (4), ELISA (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Alternatives 
