Integrin alpha 1 (ITGA1) antibody (Alexa Fluor 647)

Antigen: Integrin alpha 1 (ITGA1)

Synonyms: VLA1, CD49a, HsT18964, Vla1, CD49A, E130012M19Rik

Clonality: Monoclonal (TS2-7)

Host: Mouse

Reactivity: Human

Conjugate: Alexa Fluor 647

Application: Flow Cytometry (FACS)

Catalog no.: ABIN312025

Additional Information

Alternative name: CD49a

Immunogen: Human CTL line

Isotype: IgG1, kappa

Clone: TS2-7

Description: CD49a is a 200 kD type I transmembrane glycoprotein, also known as alpha1 integrin, VLA-1 alpha chain, or Integrin alpha1. Itassociates with CD29 (beta1 integrin) to form VLA-1 complex, a collagen IV and alminin-1 receptor and that is expressedon activated T cells, monocytes, NK cells, smooth muscle cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration and T cell proliferation andcytokine production.

Application Details

Application Notes: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor

Purification: The antibody was purified by affinity chromatography, and conjugated withAlexa Fluor 647 under optimal conditions. The solution is free of unconjugated Alexa Fluor 647.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).

Storage: The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.

Restrictions: For Research Use only