CD101 Molecule (CD101) antibody (APC)

Antigen: CD101 Molecule (CD101)

Synonyms: V7, CD101

Clonality: Monoclonal (BB27)

Host: Mouse

Reactivity: Human

Conjugate: APC

Application: Flow Cytometry (FACS)

Catalog no.: ABIN312029

Additional Information

Alternative name: CD101 (BB27)

Isotype: IgG1, kappa chain

Clone: BB27

Description: CD101 is a type I transmembrane glycoprotein, known as V7, and P126. It is a 120 kD homodimer, the member ofEWI family within Ig superfamily. CD101 is found on monocytes, granulocytes, dendritic cells, a subpopulation ofperipheral blood T cells and activated T cells. It has been reported that CD101 expressing Tregs posses higherinhibitory function. The biological function of CD101 is still not clear. But it has been found that BB27 antibody is ableto inhibit T cell proliferative responses and this inhibitory function can be overcome by high doses of IL-2. Activation ofCD101 on dendritic cells is able to induce IL-10 production.

Application Details

Application Notes: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 ul per million cells or 20 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application. Additonal reported application: include immunoprecipitation, immunohiochemal staining on acetone-fixed frozentissue sections

Purification: The antibody was purified by affinity chromatography, and conjugated withAPC under optimal conditions. The solution is free of unconjugated APC andunconjugated antibody.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).

Storage: The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.

Restrictions: For Research Use only