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Antibodies
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anti-Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) antibody (APC)
Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) antibody (APC)
| Antigen |
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| Synonyms |
IFNAR1, IFNAR1E, IFNAR, ifnar1 |
| Clonality |
Monoclonal (MAR1-5A3) |
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Host
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Reactivity
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Human (28), Mouse (Murine) (20), Rat (Rattus) (19), Cow (Bovine) (6), Pig (Porcine) (3), Dog (Canine) (2), Rabbit (2), Sheep (Ovine) (2), Chicken (1), Guinea Pig (1), Horse (Equine) (1)
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Conjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Application
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Flow Cytometry (FACS) (20), Immunofluorescence (IF) (18), Western Blotting (WB) (12), ELISA (4), Enzyme Immunoassay (EIA) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunoprecipitation (IP) (3), ELISA (Detection) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
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| Catalog no. |
ABIN312119 |
| Quantity |
25 ug (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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IFNAR-1
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Immunogen
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plasmid DNA encoding murine IFNAR1 extracellular domain
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Isotype
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IgG1, kappa chain
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Clone
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MAR1-5A3
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Description
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IFNAR-1, the type I IFN receptor subunit 1 is coexpressed with IFNAR-2 on nearly all cells and make up theheterodimeric receptor complex that binds to all type I IFNs (IFN-alpha/beta). Type I IFNs are a group of structurally andfunctionally related cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor and autoimmuneresponses. Ligand binding to the IFN-alpha/beta receptor complex leads to the tyrosine phosphorylation and activation ofIFNAR-1-associated Tyk2 and IFNAR-2-associated Jak1 signal transductions.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is approx. 0.25 ug per 106 cells in 100 ul volume. It isrecommended that the reagent be titrated for optimal performance for each application.
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Purification
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The antibody was purified by affinity chromatography, and conjugated withAPC under optimal conditions. The solution is free of unconjugated APC andunconjugated antibody.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
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Storage
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1)", type "Antibodies"
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Hosts
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Rabbit (27), Mouse (2), Goat (1)
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Reactivities
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Human (28), Mouse (Murine) (20), Rat (Rattus) (19), Cow (Bovine) (6), Pig (Porcine) (3), Dog (Canine) (2), Rabbit (2), Sheep (Ovine) (2), Chicken (1), Guinea Pig (1), Horse (Equine) (1)
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Applications
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Flow Cytometry (FACS) (20), Immunofluorescence (IF) (18), Western Blotting (WB) (12), ELISA (4), Enzyme Immunoassay (EIA) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunoprecipitation (IP) (3), ELISA (Detection) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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Center (1), pSer 535/539 (1)
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Alternatives 
