CD200 Molecule (CD200) antibody (Biotin)

Antigen: CD200 Molecule (CD200)

Synonyms: CD200, Mox2, Cspmo2, MRCOX2, MGC108657, MOX2, MGC128080, DKFZp459C0716, MRC, MOX1, OX-2, ox2g

Clonality: Monoclonal (OX-104)

Host: Mouse

Reactivity: Human

Conjugate: Biotin

Application: Flow Cytometry (FACS)

Catalog no.: ABIN312170

Additional Information

Alternative name: CD200 (OX2)

Isotype: IgG1, kappa chain

Clone: OX-104

Description: CD200, also known as OX2, is a member of the immunoglobulin superfamily (IgSF). It is a monomorphic cell surfaceglycoprotein that is expressed on thymocytes, neurons, endothelium, follicular dendritic cells in all lymphoid organs, asubset of CD34+ progenitor cells and at low levels on some smooth muscle and B lymphocytes, but not on NK cells,monocytes, granulocytes, or platelets. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity ina variety of tissues. The interaction between CD200 (OX2) and CD200 receptor (OX2R) system is of importance inthe control of macrophage and granulocyte activation, which may contribute to pathways that suppress and limitmacrophage induced inflammatory damage in tissue.

Application Details

Application Notes: Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is approx. 0.25 ug per 106 cells in 100 ul volume or100 ul of whole blood. It is recommended that the reagent be titrated foroptimal performance for each application. Additional reported applications (for the relevant formats) include: blocking the interaction of CD200 with CD200R.

Purification: The antibody was purified by affinity chromatography, and conjugated withbiotin under optimal conditions. The solution is free of unconjugated biotin.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Storage: The antibody solution should be stored undiluted at 4 degrees C. Do not freeze.

Restrictions: For Research Use only