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CD231 (TALLA) antibody (Biotin)

Antigen

CD231 (TALLA)

Clonality Monoclonal (SN1a(M3-3D9))
Host

Mouse

Reactivity

Human

Conjugate
Biotin
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC)
Catalog no. ABIN312178
Quantity 25 ug  (Variants)
Price Product not available in this region.
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Additional Information

Immunogen isolated human CD231 antigen
Isotype IgG1, kappa chain
Clone SN1a(M3-3D9)
Description CD231 is 150 kD (28-45 kD reduced) cell surface glycoprotein belonging to the Transmembrane 4 Superfamily(TM4SF also known as tetraspanins). It was originally described as T-cell Acute Lymphoblastic Leukemia Antigen(TALLA or TALLA-1). CD231 is expressed on T-cell acute lymphoblastic leukemia, neuroblastoma cells, skeletalmuscle, spleen and normal brain neuron. CD231 plays a role in integrin-mediated migration, however, its biologicalfunction is not fully clear yet.

Application Details

Application Notes Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is approx. 1.0 ug per 106 cells in 100 ul volume or 100 ul ofwhole blood. It is recommended that the reagent be titrated for optimal performance for each application. Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunohistochemicalstaining of acetone-fixed frozen tissue sections1, immunofluorescence2
Purification The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. Thesolution is free of unconjugated biotin and unconjugated antibody.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Storage The antibody solution should be stored undiluted at 4 degrees C. Do not freeze.
Restrictions For Research Use only