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Antibodies
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anti-Toll-Like Receptor 1 (TLR1) antibody (Biotin)
Toll-Like Receptor 1 (TLR1) antibody (Biotin)
| Antigen |
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| Synonyms |
TIL, CD281, rsc786, KIAA0012, MGC104956, MGC126311, MGC126312, DKFZp547I0610, DKFZp564I0682 |
| Clonality |
Monoclonal (TLR1-136) |
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Host
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Reactivity
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Conjugate
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PE (5), Biotin (3), FITC (3), Alexa Fluor 488 (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1), RPE (1)
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Application
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Flow Cytometry (FACS) (44), Western Blotting (WB) (33), Immunofluorescence (IF) (19), Enzyme Immunoassay (EIA) (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), ELISA (5), Immunohistochemistry (Frozen Sections) (IHC (fro)) (5), Immunoprecipitation (IP) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (IHC) (2), Dot Blot (Dot) (1), Immunoelectron Microscopy (IEM) (1)
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| Catalog no. |
ABIN312186 |
| Quantity |
25 ug (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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CD281 (TLR1)
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Immunogen
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Human TLR1 transfected Ba/F3
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Isotype
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IgG1, kappa chain
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Clone
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TLR1-136
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Description
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Toll-like receptors (TLRs) are type I transmembrane signaling receptors characterized by containing leucine-richrepeats (LRR) extracellular domain and IL-1 receptor like intracellular domain. TLRs are responsible for recognizingpathogen-associated molecule patterns (PAMPs). They are primary sensors of both innate and adaptive immunesystems. To date a total of 12 TLRs have been indentified. Toll-like receptor 1 (TLR1), known as CD281, is expressedon monocytes/macrophages, dendritic cells, and granulocytes and some lymphocytes at low levels. By associationwith TLR2, TLR1 is a coreceptor involved in the response to diverse set of pathogens, such as triacylatedlipopeptidess (but not diacylated lipopeptides), peptidoglycans, lipoteichoic acid.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is approx. 2.0 ug per 106 cells in 100 ul volume. It isrecommended that the reagent be titrated for optimal performance for eachapplication. Other reported applications include immunoprecipitation1
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Purification
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The antibody was purified by affinity chromatography, and conjugated withbiotin under optimal conditions. The solution is free of unconjugated biotinand unconjugated antibody.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
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Storage
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The antibody solution should be stored undiluted at 4 degrees C. Do not freeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "Toll-Like Receptor 1 (TLR1)", type "Antibodies"
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Hosts
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Rabbit (47), Mouse (20), Goat (5), Rat (1)
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Reactivities
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Human (66), Mouse (Murine) (35), Rat (Rattus) (22), Cow (Bovine) (16), Dog (Canine) (16), Horse (Equine) (16)
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Applications
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Flow Cytometry (FACS) (44), Western Blotting (WB) (33), Immunofluorescence (IF) (19), Enzyme Immunoassay (EIA) (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), ELISA (5), Immunohistochemistry (Frozen Sections) (IHC (fro)) (5), Immunoprecipitation (IP) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (IHC) (2), Dot Blot (Dot) (1), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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PE (5), Biotin (3), FITC (3), Alexa Fluor 488 (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1), RPE (1)
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Epitopes
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N-Term (6), AA 400-450 (2), internal (1)
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Alternatives 
