MSC and NPC (W4A5) antibody (Biotin)

Antigen: MSC and NPC (W4A5)

Clonality: Monoclonal (W4A5)

Host: Mouse

Reactivity: Human

Conjugate: Biotin

Application: Flow Cytometry (FACS)

Catalog no.: ABIN312246

Additional Information

Immunogen: Retinoblastoma cell line (Weri-RB-1 cells)

Isotype: IgG1, kappa chain

Clone: W4A5

Description: The W4A5 antibody was generated by immunization with Weri-RB-1 cells. It reacts with a subpopulation ofmesenchymal stem cells and neural progenitor cells (NPCs). Mesenchymal stem cells or MSCs wereoriginally designated as bone marrow stromal cells. They are a population of adult stem cells with a large capacity forself-renewal and multipotency for differentiation into a variety of cell types including osteoblasts, chondrocytes,myocytes, adipocytes, beta-pancreatic islets cells and certain neuronal cells. MSCs reside in many tissues, such as bonemarrow, placenta, adipose tissue, adult peripheral blood, fetal blood, skin, as well as liver and lung. Besides theirplasticity for tissue repair, MSCs also exhibit a powerful immunosuppressive activity and play important role insupporting hematopoiesis. NPCs can give rise to astrocytes, neurons, and oligodendrocytes

Application Details

Application Notes: Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is approx. 0.5 ug per 106 cells in 100 ul volume or100 ul of whole blood. It is recommended that the reagent be titrated foroptimal performance for each application.

Purification: The antibody was purified by affinity chromatography, and conjugated withbiotin under optimal conditions. The solution is free of unconjugated biotin.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Storage: The antibody solution should be stored undiluted at 4 degrees C. Do not freeze.

Restrictions: For Research Use only