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Antibodies
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anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody (Biotin)
Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody (Biotin)
| Antigen |
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| Synonyms |
5HT1a, 5-HT1A, ADRBRL1, ADRB2RL1, RDC1, CMKOR1, GPR159, anon-WO0170980.16, anon-WO0170980.17, anon-WO0170981.1, BEST:LD12308, CG3171, DmelCG3171, LD12308, sctt, tre-1, Tre-1, tre1 |
| Clonality |
Monoclonal (8F11-M16) |
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Host
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Reactivity
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Conjugate
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PE (2), APC (1), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), CF (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Application
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Immunofluorescence (IF) (20), Western Blotting (WB) (8), Flow Cytometry (FACS) (6), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Enzyme Immunoassay (EIA) (3), ELISA (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)
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| Catalog no. |
ABIN312319 |
| Quantity |
25 ug (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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CXCR7
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Immunogen
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human CXCR7 transfectant
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Isotype
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IgG2b, kappa chain
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Clone
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8F11-M16
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Description
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CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large proteinfamily of G protein-coupled receptors (GPCR). CXCR7 binds with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC,which regulates the trafficking and activation of leukocytes. It is also a co-receptor for the entry of HIV-1. Binding ofligand to CXCR7 induces proliferation and migration of immature neurons, glia and their precursors. CXCR7expression occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendriticcells. Surface expression of CXCR7 was also reported to be on tumor cells, activated endothelial cells, fetal livercells, and few other cell types.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is approx. 2.0 ug per 106 cells in 100 ul volume or100 ul of whole blood. It is recommended that the reagent be titrated foroptimal performance for each application.
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Purification
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The antibody was purified by affinity chromatography, and conjugated withbiotin under optimal conditions. The solution is free of unconjugated biotin.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
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Storage
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The antibody solution should be stored undiluted at 4 degrees C. Do not freeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "Chemokine (C-X-C Motif) Receptor 7 (CXCR7)", type "Antibodies"
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Hosts
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Rabbit (25), Mouse (5)
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Reactivities
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Human (30), Mouse (Murine) (22), Rat (Rattus) (19), Cow (Bovine) (16), Chicken (15), Rabbit (15), Horse (Equine) (1), Monkey (1)
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Applications
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Immunofluorescence (IF) (20), Western Blotting (WB) (8), Flow Cytometry (FACS) (6), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Enzyme Immunoassay (EIA) (3), ELISA (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)
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Conjugates
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PE (2), APC (1), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), CF (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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C-Term (2), N-Term (1)
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Alternatives 
