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Antibodies
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anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (FITC)
Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (FITC)
| Antigen |
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| Synonyms |
LAMPA, CD107a, LGP120 |
| Clonality |
Monoclonal (H4A3) |
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Host
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Reactivity
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Conjugate
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Application
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Flow Cytometry (FACS) (71), Western Blotting (WB) (36), Immunoprecipitation (IP) (23), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Immunofluorescence (IF) (10), Immunocytochemistry (ICC) (8), Immunohistochemistry (IHC) (5), ELISA (2), ELISA (Detection) (2), Enzyme Immunoassay (EIA) (2), Immunoelectron Microscopy (EM) (1)
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| Catalog no. |
ABIN312387 |
| Quantity |
25 tests (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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CD107a
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Isotype
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IgG1, kappa chain
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Clone
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H4A3
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Description
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CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type Imembrane gly-coprotein. The mature CD107a is heavily glycosylated from a 40 kD core protein. It is expressed byactivated platelets, acti-vated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells.This molecule is located on the luminal side of lysosomes and has been suggested to play a role in the protection oflysosome membrane from lysosomal hydrolases. Upon activation, CD107a is transferred to the cell membranesurface. It plays a role in cell adhesion and regula-tion of tumor metastasis, and mediates autoimmune diseaseprogression. CD107a is a ligand for galaptin and E-selectin.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 ul per million cells or 20 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application. Additional reported applications (for the relevant formats) include: Western blotting and immunohistochemical staining2.
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Purification
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The antibody was purified by affinity chromatography, and conjugated withFITC under optimal conditions. The solution is free of unconjugated FITC andunconjugated antibody.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
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Storage
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "Lysosomal-Associated Membrane Protein 1 (LAMP1)", type "Antibodies"
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Hosts
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Mouse (62), Rat (24), Rabbit (12)
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Reactivities
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Human (59), Mouse (Murine) (30), Rat (Rattus) (13), Pig (Porcine) (6), Hamster (5), Primate (2)
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Applications
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Flow Cytometry (FACS) (71), Western Blotting (WB) (36), Immunoprecipitation (IP) (23), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Immunofluorescence (IF) (10), Immunocytochemistry (ICC) (8), Immunohistochemistry (IHC) (5), ELISA (2), ELISA (Detection) (2), Enzyme Immunoassay (EIA) (2), Immunoelectron Microscopy (EM) (1)
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Conjugates
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FITC (14), PE (14), APC (10), Biotin (8), Cy5,PE (3), SPRD (2), Alexa Fluor 488 (1), RPE (1)
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Epitopes
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C-Term (1), N-Term (1)
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Alternatives 
