T-Cell Receptor (TCR), gamma/delta- antibody (FITC)

Antigen: T-Cell Receptor (TCR), gamma/delta-

Clonality: Monoclonal (B1)

Host: Mouse

Reactivity: Human

Conjugate: FITC

Application: Flow Cytometry (FACS)

Catalog no.: ABIN312466

Additional Information

Alternative name: TCR gamma/delta

Isotype: IgG1, kappa chain

Clone: B1

Description: T cell receptor (TCR) is a heterodimer consisting of an alpha and a beta chain (TCR alpha/beta) or a gamma and a delta chain (TCR gamma/delta). TCRgamma/delta is involved in the recognition of certain bacterial, self-CD1 molecule, and tumor antigens bound to MHC class I.The gamma/delta TCR associates with CD3 and is expressed on a subset of T cells found in the thymus, the intestinalepithelium, and the peripheral lymphoid tissues and peritoneum. Most gamma/delta T cells are CD4-/CD8-, some are CD8+. Tcells expressing the gamma/delta TCR have been shown to play a role in oral tolerance, innate immune response for sometumor cells, and autoimmune disease. It has been reported that gamma/delta T cells also play a principal role in antigenpresentation.

Application Details

Application Notes: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is approx. 0.5 ug per 106 cells in 100 ul volume or 100 ul ofwhole blood. It is recommended that the reagent be titrated for optimal performance for each application. 1.Rodriguez-Gago, M., et al., 2001. Transplantation. 72: 5032.Lehmann, FS., et al., 2002. Am J Physiol Gastrointest Liver Physiol 283: G481-G488

Purification: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. Thesolution is free of unconjugated FITC.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Storage: The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do notfreeze.

Restrictions: For Research Use only