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Thymic Stromal Lymphopoietin (TSLP) antibody

Antigen

Thymic Stromal Lymphopoietin (TSLP)

Synonyms TSLP
Clonality Monoclonal (13H8-3)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Application
Alternatives Neutralization (Neut)
Catalog no. ABIN312648
Quantity 50 ug  (Variants)
Price Product not available in this region.
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Additional Information

Alternative name TSLP
Isotype IgG1, kappa chain  (Matching secondary antibodies)
Clone 13H8-3
Description Thymic Stromal Lymphopoietin (TSLP) is a hemopoietic protein that is expressed in the heart, liver and prostate.TSLP overlaps biological activities with IL-7 and binds with the heterodimeric receptor complex consisting of the IL-7Ralpha chain (IL-7Ralpha) and the TSLP-specific chain (TSLPR). Like IL-7, TSLP induces phosphorylation of STAT3 andSTAT5, but uses kinases other than the JAKs for activation. TSLP prohibited apoptosis and stimulated growth of thehuman acute myeloid leukemia (AML)-derived cell line MUTZ3. It induces the release of T cell-attracting chemokinesTARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs). TSLP activated DCs primed na

Application Details

Application Notes Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA detection antibody, aconcentration range of 0.5-2 ug/ml is recommended. To obtain a linear standard curve, serial dilutions of TSLPrecombinant protein ranging from 200 to 3.1 ng/ml are recommended for each ELISA plate. It is recommended thatthe reagent be titrated for optimal performance for each application.
Purity LEAF Purified
Purification The antibody was purified by affinity chromatography.
Buffer Phosphate-buffered solution, pH 7.2, containing no preservative. 0.2 um filter sterilized. Endotoxin level is < 0.1 EU/ug of the protein (< 0.01 ng/ug of the protein) as determined by the LAL test.
Storage The antibody solution should be stored undiluted at 4 degrees C.
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Thymic Stromal Lymphopoietin (TSLP)", type "Antibodies"
Hosts Rabbit (45), Mouse (4), Rat (1)
Reactivities Human (46), Mouse (Murine) (7), Rat (Rattus) (3), Dog (Canine) (1), Monkey (1)
Applications Flow Cytometry (FACS) (24), Western Blotting (WB) (24), Immunofluorescence (IF) (23), ELISA (16), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Enzyme Immunoassay (EIA) (7), Immunoprecipitation (IP) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Blocking Antibody (Inhibition) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Biotin (7), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Alexa Flour 488 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)