»
Antibodies
»
anti-Thymic Stromal Lymphopoietin (TSLP) antibody
Thymic Stromal Lymphopoietin (TSLP) antibody
| Antigen |
|
| Synonyms |
TSLP |
| Clonality |
Monoclonal (13H8-3) |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
|
| Catalog no. |
ABIN312648 |
| Quantity |
50 ug (Variants) |
| Price |
Product not available in this region.
|
| Shipping to |
|
|
Alternative name
|
TSLP
|
|
Isotype
|
IgG1, kappa chain (Matching secondary antibodies)
|
|
Clone
|
13H8-3
|
|
Description
|
Thymic Stromal Lymphopoietin (TSLP) is a hemopoietic protein that is expressed in the heart, liver and prostate.TSLP overlaps biological activities with IL-7 and binds with the heterodimeric receptor complex consisting of the IL-7Ralpha chain (IL-7Ralpha) and the TSLP-specific chain (TSLPR). Like IL-7, TSLP induces phosphorylation of STAT3 andSTAT5, but uses kinases other than the JAKs for activation. TSLP prohibited apoptosis and stimulated growth of thehuman acute myeloid leukemia (AML)-derived cell line MUTZ3. It induces the release of T cell-attracting chemokinesTARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs). TSLP activated DCs primed na
|
|
Application Notes
|
Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA detection antibody, aconcentration range of 0.5-2 ug/ml is recommended. To obtain a linear standard curve, serial dilutions of TSLPrecombinant protein ranging from 200 to 3.1 ng/ml are recommended for each ELISA plate. It is recommended thatthe reagent be titrated for optimal performance for each application.
|
|
Purity
|
LEAF Purified
|
|
Purification
|
The antibody was purified by affinity chromatography.
|
|
Buffer
|
Phosphate-buffered solution, pH 7.2, containing no preservative. 0.2 um filter sterilized. Endotoxin level is < 0.1 EU/ug of the protein (< 0.01 ng/ug of the protein) as determined by the LAL test.
|
|
Storage
|
The antibody solution should be stored undiluted at 4 degrees C.
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "Thymic Stromal Lymphopoietin (TSLP)", type "Antibodies"
|
Hosts
|
Rabbit (45), Mouse (4), Rat (1)
|
|
Reactivities
|
Human (46), Mouse (Murine) (7), Rat (Rattus) (3), Dog (Canine) (1), Monkey (1)
|
|
Applications
|
Flow Cytometry (FACS) (24), Western Blotting (WB) (24), Immunofluorescence (IF) (23), ELISA (16), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Enzyme Immunoassay (EIA) (7), Immunoprecipitation (IP) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Blocking Antibody (Inhibition) (1), Immunoelectron Microscopy (IEM) (1)
|
|
Conjugates
|
Biotin (7), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Alexa Flour 488 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
|