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Chemokine (C-C Motif) Receptor 5 (CCR5) antibody

Antigen

Chemokine (C-C Motif) Receptor 5 (CCR5)
Synonyms CKR5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5, FLJ78003, Ckr5, Cmkbr5, CCR5, CCR1-L, GPCR, MGC137803, CCR-5, AM4-7, CCR2, CCR5-L
Clonality Monoclonal (HM-CCR5)
Host
Alternatives

Hamster
Reactivity
Alternatives

Mouse (Murine)
Application
Alternatives Flow Cytometry (FACS)
Catalog no. ABIN312663
Quantity 500 ug  (Variants)
Price Product not available in this region.
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Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Alternative name CD195 (CCR5)
Isotype IgG  (Matching secondary antibodies)
Clone HM-CCR5
Description CD195 is a 45 kD chemokine receptor also known as CCR5. CD195 is a seven transmembrane-spanning Gprotein-associated molecule expressed on macrophages, a T cell subset, and in the heart, liver, and spleen. CD195regulates lymphocyte chemotaxis and transendothelial migration during inflammatory processes. CD195 interacts withseveral ligands including RANTES, MCP-1, MIP-1alpha, and MIP-1beta.

Application Details
Alternatives Secondary Antibodies Variants back to top

Application Notes Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is approx. 0.5 ug per 106 cells in 100 ul volume. It isrecommended that the reagent be titrated for optimal performance for each application. CCR5 is expressed at low density on activated cells. For most successful immunofluorescent staining results, it maybe important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat.No. 107006) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat.No. 107004) or biotinylated anti-Armenian hamster IgG (Cat. No. 405501) second step, followed by SAv-PE (Cat. No. 405204)).
Purity LEAF Purified
Purification The antibody was purified by affinity chromatography.
Buffer Phosphate-buffered solution, pH 7.2, containing no preservative. 0.2 um filter sterilized. Endotoxin level is < 0.1 EU/ug of the protein (< 0.01 ng/ug of the protein) as determined by the LAL test.
Storage The antibody solution should be stored undiluted at 4 degrees C.
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "Chemokine (C-C Motif) Receptor 5 (CCR5)", type "Antibodies"
Hosts Rabbit (45), Rat (27), Mouse (21), Hamster (13), Goat (1)
Reactivities Human (87), Mouse (Murine) (33), Rat (Rattus) (20), Cow (Bovine) (2), Dog (Canine) (1), Zebrafish (Brachydanio rerio) (1)
Applications Flow Cytometry (FACS) (76), Western Blotting (WB) (30), Immunofluorescence (IF) (26), ELISA (12), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (12), Enzyme Immunoassay (EIA) (8), Immunohistochemistry (IHC) (4), Immunoprecipitation (IP) (4), ELISA (Detection) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Functional Studies (Func) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates PE (12), Biotin (7), FITC (6), RPE (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes N-Term (2), non pSer337/349 (1), pSer337 (1), pSer349 (1)