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Antibodies
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anti-CD45RA (CD45RA) antibody (Pacific Blue)
CD45RA (CD45RA) antibody (Pacific Blue)
| Antigen |
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| Clonality |
Monoclonal (HI100) |
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Host
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Reactivity
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Conjugate
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FITC (25), PE (17), Biotin (13), RPE (7), APC (5), Cy5,PE (5), Cy5.5 (2), Cy7,PE (2), Pacific Blue (2), Alexa Fluor 488 (1), Alexa Fluor 700 (1), Cy5.5,PE (1), PE,DY647 (1), PE-Dyomics 647 (1), PerCP (1), RPE,Cy5 (1)
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Application
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| Catalog no. |
ABIN312738 |
| Quantity |
100 tests (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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CD45RA
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Isotype
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IgG2b, kappa chain
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Clone
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HI100
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Description
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CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphataseCD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes.CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates withlymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to beassociated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reportedto bind galectin-1. CD45 isoform expression can change in response to cytokines.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.
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Purification
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The antibody was purified by affinity chromatography, and conjugated with Pacific Blue
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
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Storage
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do notfreeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "CD45RA (CD45RA)", type "Antibodies"
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Hosts
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Mouse (144)
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Reactivities
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Human (117), Rat (Rattus) (16), Pig (Porcine) (8), Dog (Canine) (3)
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Applications
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Flow Cytometry (FACS) (123), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (51), Immunohistochemistry (Frozen Sections) (IHC (fro)) (29), Immunoprecipitation (IP) (19), Western Blotting (WB) (16), Immunofluorescence (IF) (7), Immunohistochemistry (IHC) (7), Immunocytochemistry (ICC) (3), ELISA (1)
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Conjugates
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FITC (25), PE (17), Biotin (13), RPE (7), APC (5), Cy5,PE (5), Cy5.5 (2), Cy7,PE (2), Pacific Blue (2), Alexa Fluor 488 (1), Alexa Fluor 700 (1), Cy5.5,PE (1), PE,DY647 (1), PE-Dyomics 647 (1), PerCP (1), RPE,Cy5 (1)
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Alternatives 
