Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) antibody (PE)

Antigen: Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1)

Synonyms: MGC69188, PVRL1, prr1, pvrl1, ED4, PRR, HIgR, HVEC, OFC7, PRR1, PVRR, CD111, PVRR1, SK-12, CLPED1, MGC16207, nectin-1, MGC142031, HveC, Cd111, AI835281, AW549174

Clonality: Monoclonal (R1-302)

Host: Mouse

Reactivity: Human

Conjugate: PE

Application: Flow Cytometry (FACS)

Catalog no.: ABIN312790

Additional Information

Alternative name: CD111 (Nectin-1)

Immunogen: Human Nectin-1 transfected NIH/3T3 cells

Isotype: IgG1, kappa chain

Clone: R1-302

Description: CD111, known as poliovirus receptor related 1 protein (PRR1), Nectin-1 and HveC, is a 75 kD type I transmembraneglycoprotein. A member of the nectin family and Ig gene superfamily, CD111 is broadly expressed on endothelialcells, epithelial cells, neuronal cells, megakaryocytes, and CD34-positive stem cells. CD111 functions as one of theherpes simplex virus 1 (HSV-1) and HSV-2 receptors and is an adhesion molecule involved in the formation of celljunction.

Application Details

Application Notes: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 ul per 106 cells in 100 ul volume or 100 ul ofwhole blood. It is recommended that the reagent be titrated for optimal performance for each application. Additional reported applications (for relevant formats) include: immunoprecipitation, Western blot,immunohistochemical staining of frozen tissue sections, block HSV-1 and HSV-2 entry into cells

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solutionis free of unconjugated PE and unconjugated antibody.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Storage: The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do notfreeze.

Restrictions: For Research Use only