CD300e Molecule (CD300E) antibody (PE)

Antigen: CD300e Molecule (CD300E)

Clonality: Polyclonal

Host: Please enquire

Reactivity: Human

Conjugate: PE

Application: Flow Cytometry (FACS)

Catalog no.: ABIN312949

Additional Information

Alternative name: IREM-2 (CD300e, CMRF35-A5)

Immunogen: IREM-IgG fusion protein

Isotype: IgG1, kappa chain

Clone: UP-H2

Description: IREM-2 (immune receptor expressed by myeloid cells 2), also known as CMRF35-A5, LMIR6, CD300Le or CD300e,is a 34 kDa type I single transmembrane glycoprotein. It is a member of the CD300 family and of the Ig-superfamily.IREM-2 is expressed on monocyte and myeloid dendritic cells, but not on granulocytes and lymphoid dendritic cells.IREM-2 is an activating receptor through interaction with DAP12.

Application Details

Application Notes: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 ul per million cells or 20 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application. Additional reported applications include: immunoprecipitation and stimulation of TNF-a production by monocytes

Purification: The antibody was purified by affinity chromatography, and conjugated withPE under optimal conditions. The solution is free of unconjugated PE andunconjugated antibody.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).

Storage: The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.

Restrictions: For Research Use only

Publications

Publications: Aguilar, Alvarez-Errico, Garcuia-Montero et al.: "Molecular characterization of a novel immune receptor restricted to the monocytic lineage." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 11, pp. 6703-11, 2004 (PubMed).