»
Antibodies
»
anti-Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) antibody (PE)
Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) antibody (PE)
| Antigen |
|
| Synonyms |
CVID, TACI, CD267, FLJ39942, MGC39952, MGC133214, TNFRSF14B, TNFRSF13B |
| Clonality |
Monoclonal (8F10) |
|
Host
|
|
|
Reactivity
|
|
|
Conjugate
|
Biotin (3), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
|
|
Application
|
Flow Cytometry (FACS) (24), Immunofluorescence (IF) (21), Western Blotting (WB) (17), Enzyme Immunoassay (EIA) (6), ELISA (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoprecipitation (IP) (2), Functional Studies (Func) (1), Immunoelectron Microscopy (IEM) (1)
|
| Catalog no. |
ABIN313025 |
| Quantity |
50 ug (Variants) |
| Price |
Product not available in this region.
|
| Shipping to |
|
|
Alternative name
|
CD267 (TACI)
|
|
Immunogen
|
Rat RBL transfected cell lineReactivity: MouseCross-
|
|
Isotype
|
IgG2a, kappa chain
|
|
Clone
|
8F10
|
|
Description
|
Transmembrane Activator and CAML Interactor (TACI) is a tumor necrosis factor receptor superfamily (TNFSF)member. It is a type III transmembrane protein sharing a high degree of homology with B cell maturation antigen(BCMA) among TNFSF members. It binds to the ligands BAFF (BLyS) and APRIL. CD267 appears to be particularlyimportant for the regulation of B cell survival and maturation in the spleen. It is a major mediator of BAFF-dependentcostimulatory responses in peripheral B cells. Signaling through TACI may serve to down-regulate B cell activity aswell. The actual role for TACI in the mouse has still not been fully determined.
|
|
Application Notes
|
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is approx. 1 ug per 106 cells in 100 ul. It is recommendedthat the reagent be titrated for optimal performance for each application.
|
|
Purification
|
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solutionis free of unconjugated PE and unconjugated antibody.
|
|
Buffer
|
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
|
|
Storage
|
The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do notfreeze.
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B)", type "Antibodies"
|
Hosts
|
Rabbit (30), Rat (5), Goat (4)
|
|
Reactivities
|
Human (37), Mouse (Murine) (25), Rat (Rattus) (20), Cow (Bovine) (1), Dog (Canine) (1), Pig (Porcine) (1), Sheep (Ovine) (1)
|
|
Applications
|
Flow Cytometry (FACS) (24), Immunofluorescence (IF) (21), Western Blotting (WB) (17), Enzyme Immunoassay (EIA) (6), ELISA (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoprecipitation (IP) (2), Functional Studies (Func) (1), Immunoelectron Microscopy (IEM) (1)
|
|
Conjugates
|
Biotin (3), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
|
|
Epitopes
|
N-Term (1)
|
Alternatives 
