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Antibodies
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anti-CD79b Molecule, Immunoglobulin-Associated beta (CD79B) antibody (PE)
CD79b Molecule, Immunoglobulin-Associated beta (CD79B) antibody (PE)
| Antigen |
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| Synonyms |
B29, IGB, Igb, Igbeta, Ig-beta, MGC108607, CD79B, LOC100304995 |
| Clonality |
Monoclonal (HM79-12) |
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Host
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Reactivity
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Conjugate
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Application
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Flow Cytometry (FACS) (102), Western Blotting (WB) (48), Immunoprecipitation (IP) (43), Immunohistochemistry (Frozen Sections) (IHC (fro)) (25), Enzyme Immunoassay (EIA) (5), Functional Studies (Func) (5), Immunofluorescence (IF) (5), ELISA (Detection) (4), Immunohistochemistry (IHC) (4), ELISA (2), Immunocytochemistry (ICC) (2)
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| Catalog no. |
ABIN313059 |
| Quantity |
50 ug (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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CD79b
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Isotype
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IgG
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Clone
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HM79-12
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Description
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Mouse CD79b (Ig betachain) is a 35-40kDa transmembrane protein that forms aheterodimer with CD79a (30-35 kDa, Ig alpha chain). The CD79b and CD79ahererodimers are associated with surface IgM to form the B-cell receptor(BCR) that is necessary for signal transduction via the BCR in mature B cells. CD79b participates signal transduction involved in the development of Bcells as well. It was reported that association between CD79b/CD79a withIgM is essential in inducing both the transition from progenitor to precursor Bcells and subsequent allelic exclusion. Ig beta knockout mice had a completeblock in B cell development at the immature CD43+B220+ stage. TheHM79b-12 react with an extracellular epitope of CD79b or Ig beta.
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Application Notes
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Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is approx. 1.0 ug per 106 cells in 100 ul volume or100 ul of whole blood. It is recommended that the reagent be titrated foroptimal performance for each application.
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Purification
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The antibody was purified by affinity chromatography, and conjugated withPE under optimal conditions. The solution is free of unconjugated PE andunconjugated antibody.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
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Storage
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "CD79b Molecule, Immunoglobulin-Associated beta (CD79B)", type "Antibodies"
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Hosts
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Hamster (53), Mouse (51), Rat (8), Rabbit (2)
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Reactivities
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Human (60), Mouse (Murine) (57), Dog (Canine) (5), Pig (Porcine) (4), Rat (Rattus) (4)
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Applications
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Flow Cytometry (FACS) (102), Western Blotting (WB) (48), Immunoprecipitation (IP) (43), Immunohistochemistry (Frozen Sections) (IHC (fro)) (25), Enzyme Immunoassay (EIA) (5), Functional Studies (Func) (5), Immunofluorescence (IF) (5), ELISA (Detection) (4), Immunohistochemistry (IHC) (4), ELISA (2), Immunocytochemistry (ICC) (2)
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Conjugates
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FITC (26), PE (19), Biotin (9), RPE (5), APC (3), SPRD (2), Cy5,PE (1)
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Alternatives 
