Chemokine (C-X-C Motif) Receptor 5 (CXCR5) antibody (PerCP/Cy5.5)

Antigen: Chemokine (C-X-C Motif) Receptor 5 (CXCR5)

Synonyms: BLR1, CD185, MDR15, MGC117347, NLR, Blr1, CXCR5, CRL1

Clonality: Monoclonal (TG2-CXCR5)

Host: Mouse

Reactivity: Human

Conjugate: PerCP,Cy5.5

Application: Flow Cytometry (FACS)

Catalog no.: ABIN313315

Additional Information

Alternative name: CD185 (CXCR5)

Isotype: IgG2b, kappa chain

Clone: TG2-CXCR5

Description: CXCR5 is a chemokine receptor which binds to CXCL13. CXCR5 is expressed in B cells and T folicular helper (TFH)cells (1). CXCR5 is required for migration of B cells to the follicular compartment in the spleen, lymph nodes,Peyer',s patches, and tonsils, and normal maturation of primary follicle follicular dendritic cells (2, 3). CXCR5 andCXCL13 contribute in the B cell homing to Peyer',s patches (4). In addition, T cell CXCR5 is required for germinalcenter response of normal magnitude (5).

Application Details

Application Notes: Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is 5 ul per million cells or 20 ul per 100 ul ofwhole blood. It is recommended that the reagent be titrated for optimalperformance for each application. * PerCP/Cy5.5 has a maximum absorption of 482 nm and 564 nm and amaximum emission of 690 nm.

Purification: The antibody was purified by affinity chromatography, and conjugated withPerCP/Cy5.5 under optimal conditions. The solution is free of unconjugatedPerCP/Cy5.5 and unconjugated antibody.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).

Storage: The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.

Restrictions: For Research Use only

Images

anti-Chemokine (C-X-C Motif) Receptor 5 (CXCR5) antibody (PerCP/Cy5.5)