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Antibody
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anti-B-Cell Leukemia-lymphoma 10 BCL10
B-Cell Leukemia/lymphoma 10 (BCL10) antibody
| Antigen |
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| Synonyms |
CLAP, ME10, cE10, CIPER, BCL-10, C81403, CARMEN, AI132454, bcl10 |
| Clonality |
Monoclonal (151) |
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Host
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Reactivity
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Application
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 Alternatives Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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| Catalog no. |
ABIN313793 |
| Quantity |
25 ug (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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Bcl10
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Immunogen
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The epitope recognized by the antibody resides within amino acids 122-168of human Bcl-10 molecule.
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Format
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Purified
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Isotype
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IgG1, kappa (Matching secondary antibodies)
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Clone
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151
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Description
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BCL10 promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. It may be anadapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Achromosomal aberration involving BCL10 is recurrent in low-grade mucosa-associated lymphoid tissue (MALTlymphoma), translocation t(1,14)(p22,q32). Defects in BCL10 are involved in various types of cancer.
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Application Notes
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Each lot of this antibody is quality control tested by Western blotting. Westernblotting, suggested working dilution(s): Use 5
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Purification
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The antibody was purified by protein G affinity chromatography
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Buffer
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This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide. Final antibody concentration is 0.5 mg/ml.
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Storage
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Upon receipt, store at 4
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Restrictions
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For Research Use only
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Alternatives for antigen "B-Cell Leukemia/lymphoma 10 (BCL10)", type "Antibodies"
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Hosts
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Mouse (11), Rabbit (5), Rat (1)
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Reactivities
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Human (17), Mouse (Murine) (2), Rat (Rattus) (2)
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Applications
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Western Blotting (WB) (16), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10), ELISA (8), Flow Cytometry (FACS) (4), Immunohistochemistry (Frozen Sections) (IHC (fro)) (4), Immunohistochemistry (IHC) (3), Immunoprecipitation (IP) (3), Immunofluorescence (IF) (1)
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Epitopes
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N-Term (1)
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