B-Cell CLL/lymphoma 3 (BCL3) antibody

Antigen: B-Cell CLL/lymphoma 3 (BCL3)

Synonyms: BCL4, D19S37, Bcl-3, AI528691, BCL9-2, DLNB11, BCL3

Clonality: Monoclonal (Ham150-3-5)

Host: Hamster

Reactivity: Mouse (Murine), Human

Application: Western Blotting (WB)

Catalog no.: ABIN313798

Additional Information

Alternative name: Bcl-3

Immunogen: Full length mouse Bcl-3 protein

Format: Purified

Isotype: IgG  (Matching secondary antibodies)

Clone: Ham150-3-5

Description: Bcl-3 is a 46 kD proto-oncogene candidate that is identified by its translocation into the immunoglobulin alpha-locus insome cases of B-cell leukemia. Due to its seven ankyrin repeats, it is closely related to I kappa B proteins. Thisprotein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers.The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop thatcontrols the nuclear residence of p50 NF-kappa B. The Ham150-5.3 clone has shown to be useful for westernblotting.

Application Details

Application Notes: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested workingdilution(s): Use 5 ug per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titratedfor optimal performance for each application.

Purification: This antibody was purified by affinity chromatography.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Storage: The antibody solution should be stored undiluted at 4 degrees C.

Restrictions: For Research Use only