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BCL2-Like 1 (BCL2L1) antibody
| Antigen | BCL2-Like 1 (BCL2L1) |
| Synonyms |
BCLX, BCL2L, Bcl-X, bcl-xL, bcl-xS, BCL-XL/S, DKFZp781P2092, BclX, Bcl2l, bcl-x, Bcl-XL, Bcl-Xs, Bcl(X)L, MGC99998, MGC113803, Bclx, bcl-X, Bcl-xl, BCL2L1, Bcl-xL, BCL-XL, bclx, xR11, bcl2l, bclxl, bc ...
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| Clonality | Monoclonal (2H12) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human, Mouse (Murine), Rat (Rattus), Pig (Porcine) |
| Application |
Alternatives Western Blotting (WB), Immunoprecipitation (IP), Intracellular Flow Cytometry (ICFC), Immunohistochemistry (IHC)
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| Catalog no. | ABIN313800 |
| Quantity | 100 ug (Variants) |
| Price | Product not available in this region. |
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Additional Information
| Alternative name | Bcl-XS/L |
| Immunogen | Amino acids: 3-14 common to human and mouse Bcl-X |
| Format | Purified |
| Isotype | IgG2a, kappa chain (Matching secondary antibodies) |
| Clone | 2H12 |
| Description | Bcl-X is one of the members of Bcl-2 family proteins, and exists in several isoforms generated by alternative splicingand plays a critical role in the control of apoptosis. The large isoform Bcl-XL (30KD) contains the highly conservedBH1 and BH2 amino acid domains and protects cells against apoptosis, whereas the short isoform, Bcl-XS (18KD)which deletes the conserved BH1/BH2 domain by alternative mRNA splicing, promotes apoptosis by interacting withBcl-XL and Bcl-2. Bcl-X(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developinglymphocytes. In contrast, Bcl-X(L) is found in tissues containing long-lived postmitotic cells, such as adult brain. Clone2H12 has been shown to be useful for western blotting and immunoprecipitation, immunohistochemistry, andimmunofluorescence of the Human, Mouse and Rat Bcl-XL and Bcl-XS proteins. |
| Synonyms | BCLX, BCL2L, Bcl-X, bcl-xL, bcl-xS, BCL-XL/S, DKFZp781P2092, BclX, Bcl2l, bcl-x, Bcl-XL, Bcl-Xs, Bcl(X)L, MGC99998, MGC113803, Bclx, bcl-X, Bcl-xl, BCL2L1, Bcl-xL, BCL-XL, bclx, xR11, bcl2l, bclxl, bcl-XL, bcl-xs, MGC69340, bcl-xl/s, bcl-xl, Bcl-xS |
Application Details
| Application Notes | Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested workingdilution(s): Use 5 ug per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titratedfor optimal performance for each application. |
| Purification | This antibody was purified by affinity chromatography. |
| Buffer | This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide at 0.5 mg/ml. |
| Storage | Upon receipt, store undiluted at 4 degrees C. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "BCL2-Like 1 (BCL2L1)", type "Antibodies"
| Hosts | Rabbit (52), Mouse (25), Sheep (3) |
| Reactivities | Human (73), Mouse (Murine) (47), Rat (Rattus) (37), Pig (Porcine) (3), Dog (Canine) (2) |
| Applications | Western Blotting (WB) (64), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (26), Immunohistochemistry (IHC) (15), Immunoprecipitation (IP) (13), Flow Cytometry (FACS) (11), Immunofluorescence (IF) (11), ELISA (9), Enzyme Immunoassay (EIA) (9), Immunohistochemistry (Frozen Sections) (IHC (fro)) (9), ELISA (Detection) (2) |
| Conjugates | Biotin (2), FITC (2), PE (2) |
| Epitopes | N-Term (5), pSer62 (4), pThr115 (3), Center (2), Ab-115 (1), Ab-47 (1), pThr47 (1) |
