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C-Fos antibody
| Antigen | C-Fos |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human, Rat (Rattus), Mouse (Murine) |
| Application |
Alternatives Western Blotting (WB)
|
| Catalog no. | ABIN313930 |
| Quantity | 100 ul (Variants) |
| Price | Product not available in this region. |
| Shipping to |
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Additional Information
| Immunogen | DMDLSGSFYAADWEC (aa. 291-304 of human c-Fos)Reactivity: HumanCross- |
| Format | Purified |
| Clone | Poly6414 |
| Description | The c-fos protein, also known as FBJ murine viral (v-fos) oncogene homolog , is a 62 kD cellular oncogene. The c-fosprotein contains a bZIP region with a DNA-binding domain and a leucine zipper domain. Together with c-jun, c-junproteins form the heterodimeric AP-1 complex that binds to the TRE elements of cellular and viral genes includingcollagenase, interleukin 2, stromelysin, SV40 and polyoma among others. c-fos is expressed in a variety of normaladult tissues and has been implicated as a critical transcription factor for skeletal formation and maintenance. Thistranscription factor is modified by phosphorylation by a number of upstream kinases and has been shown to interactwith a variety of other proteins involved in transcriptional regulation. c-fos has been implicated in the development offibrous bone dysplasia and osteosarcoma. The c-fos protein has been shown to interact with a variety of otherproteins including c-jun, TFIID, NCOA2, NFAT1, CHOP, ELK1, SRC1, and ETS1. The Poly6244 antibody recognizeshuman, rat, and mouse c-fos and has been shown to be useful for Western blotting, immunoprecipitation, andimmunohistochemistry. |
Application Details
| Application Notes | Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s):Use 10 ul per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimalperformance for each application. |
| Purification | The antibody was purified by antigen-affinity chromatography. |
| Buffer | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 50% glycerol. |
| Storage | Upon receipt, store at -20 degrees C. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "C-Fos", type "Antibodies"
| Hosts | Rabbit (43), Mouse (8), Sheep (7) |
| Reactivities | Human (48), Rat (Rattus) (31), Mouse (Murine) (27), Pig (Porcine) (17), Dog (Canine) (5), Cow (Bovine) (3), Hamster (2), Cat (Feline) (1), Chicken (1), Horse (Equine) (1), Rabbit (1) |
| Applications | Western Blotting (WB) (34), Flow Cytometry (FACS) (20), Immunofluorescence (IF) (19), Enzyme Immunoassay (EIA) (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), ELISA (6), Immunohistochemistry (Frozen Sections) (IHC (fro)) (5), Immunohistochemistry (IHC) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), Dot Blot (Dot) (1), Immunoelectron Microscopy (EM) (1) |
| Conjugates | Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |
| Epitopes | N-Term (3), pT232 (1), pThr232 (1) |
