Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I) antibody

Antigen: Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I)

Synonyms: TRIP1, EIF3S2, TRIP-1, PRO2242, eIF3-p36, eIF3-beta, 36kDa, Trip1, Eif3s2, D4Ertd632e

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN313965

Additional Information

Alternative name: eIF3I

Immunogen: Full-length human eIF3I recombinant protein

Format: Purified

Clone: Poly6383

Description: The eukaryotic translation initiation factor-3 (eIF3) is a 700 kD complex comprised of at least 13 subunits, includingeIF3I, which is essential for translation. eIF3 directly binds to the 40S ribosomal subunit and promotes the formationof the 40S preinitiation complex by promoting the binding of methionyl-tRNA and mRNA. Overexpression of eIF3I isbelieved to facilitate mTOR-dependent growth transformation. Poly6383 is useful for western blot applications.

Application Details

Application Notes: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s):Use 10 ul per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimalperformance for each application.

Purification: The antibody was purified by antigen-affinity chromatography.

Buffer: This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide and 50% glycerol.

Storage: Upon receipt, store frozen at -20uC.

Restrictions: For Research Use only