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Interleukin 12 (IL12) antibody
| Antigen | Interleukin 12 (IL12) |
| Synonyms | CLMF, NKSF, CLMF2, NKSF2, IL-12B, IL12A, p40, Il-12b, Il12p40, Il-12p40, Il12, IL12B, IL-12p40, IL-12, il12b, IL-12 p40, MGC152789, il12p40.b, zgc:152789, IL-12.p40, Il12b, LOC100217488 |
| Clonality | Monoclonal (C18-2) |
| Host |
 Alternatives Rat |
| Reactivity |
Alternatives Mouse (Murine) |
| Application |
Alternatives ELISA (Capture)
|
| Catalog no. | ABIN313997 |
| Quantity | 50 ug (Variants) |
| Price | Product not available in this region. |
| Shipping to |
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Additional Information
| Alternative name | IL-12 (p70) |
| Immunogen | CHO expressed, recombinant mouse IL-12 p70 |
| Format | Purified |
| Isotype | IgG2a, kappa chain (Matching secondary antibodies) |
| Clone | C18-2 |
| Description | Interleukin 12 (IL-12) is a heterodimeric pleiotropic 70 kD (p70) cytokine consisting of a 40 kDa (p40) subunit and a 35kDa (p35) subunit. IL-12 is a potent regulator of cell-mediated immune responses and key mediator of Th1 celldevelopment. Bioactive IL-12 is secreted by activated B lymphocytes, dendritic cells, and macrophages in responseto pathogens or upon interaction with activated T cells. IL-12 p70 stimulates cytotoxic T, NK and LAK cellproliferation, and induces IFN-gamma and TNF production in resting and activated T and NK cells. It has been suggestedthat IL-12 may have therapeutic potential as a vaccine adjuvant that promotes cellular-immunity and as an anti-tumorand anti-viral agent. |
Application Details
| Application Notes | Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA capture antibody, aconcentration range of 1-4 ug/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-12(p70)recombinant protein ranging from 500 to 4 pg/ml are recommended for each ELISA plate. It is recommended that thereagent be titrated for optimal performance for each application. ELISA Capture: The purified C18.2 antibody is useful as a capture antibody for a sandwich ELISA assay, when usedin conjunction with the biotinylated C17.8 antibody as detection antibody and recombinant mouse IL-12 p70 as thestandard. |
| Purification | The antibody was purified by affinity chromatography. |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Storage | The antibody solution should be stored undiluted at 4 degrees C. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Interleukin 12 (IL12)", type "Antibodies"
| Hosts | Goat (21), Mouse (19), Rat (11), Rabbit (4) |
| Reactivities | Human (19), Mouse (Murine) (19), Cow (Bovine) (6), Fish (2), Pig (Porcine) (2), Cat (Feline) (1), Dog (Canine) (1), Rat (Rattus) (1) |
| Applications | ELISA (44), Western Blotting (WB) (33), Functional Studies (Func) (9), Neutralization (Neut) (9), Flow Cytometry (FACS) (6), Immunohistochemistry (IHC) (2), Immunofluorescence (IF) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1) |
| Conjugates | Biotin (8) |
