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Mitogen-Activated Protein Kinase 8 (MAPK8) antibody
| Antigen | Mitogen-Activated Protein Kinase 8 (MAPK8) |
| Synonyms | JNK, JNK1, PRKM8, SAPK1, JNK1A2, JNK21B1/2, Prkm8, AI849689, Bsk, D-JNK, D-junk, DBSK/JNK, DJNK, DJNK/bsk, JNK/SAPK, Junk, SAPKa, dJUN, DmelCG5680, CG5680, T10F20.15 |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human, Mouse (Murine), Rat (Rattus) |
| Application |
Alternatives Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
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| Catalog no. | ABIN314016 |
| Quantity | 125 ul (5 Western Blots) (Variants) |
| Price | Product not available in this region. |
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Additional Information
| Alternative name | JNK1 |
| Immunogen | Peptide mapping to the carboxy terminus of human JNK1 |
| Format | Purified |
| Clone | Poly6331 |
| Description | The MAPK family includes several subgroups encompassing the extracellularsignal-regulated kinase (ERK) family, the p38 Map kinase family, and c-JunNH2-terminal kinase (JNK) family. JNK kinase group includes 3 members,JNK1, JNK2, and JNK3. JNK kinases are phosphorylated in response tovarious activations by environmental stress and pro-inflammatory cytokinesby phosphorylating a number of transcription factors, primarily components ofAP-1 such as c-Jun and ATF2 and thus regulate AP-1 transcriptional activity.JNK kinases are characterized by requirement for dual phosphorylation at aT-P-Y motif for enzymatic activation. The Poly6331 antibody has been shownto be useful for western blotting, immunoprecipitation, andimmunohistochemistry of human, mouse, and rat JNK1 p46 and JNK3 p54protein. |
Application Details
| Application Notes | Each lot of this antibody is quality control tested by Western blotting. Western blotting suggested working dilution(s): Use 25 ul per 5 ml antibodydilution buffer for each mini-gel. It is recommended that the reagent betitrated for optimal performance for each application. |
| Purification | This antibody was purified by affinity chromatography. |
| Buffer | This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide and 0.2% gelatin. |
| Storage | The antibody solution should be stored undiluted at 4 degrees C. DO NOT FREEZE. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Mitogen-Activated Protein Kinase 8 (MAPK8)", type "Antibodies"
| Hosts | Rabbit (36), Mouse (32), Sheep (2) |
| Reactivities | Human (62), Mouse (Murine) (13), Rat (Rattus) (11), Dog (Canine) (2), Caenorhabditis elegans (C. elegans) (1) |
| Applications | Western Blotting (WB) (60), Enzyme Immunoassay (EIA) (26), ELISA (11), Immunoprecipitation (IP) (11), Immunofluorescence (IF) (9), Immunohistochemistry (Frozen Sections) (IHC (fro)) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Dot Blot (Dot) (4), Immunohistochemistry (IHC) (4), ELISA (Detection) (3), Functional Studies (Func) (1) |
| Conjugates | Biotin (1) |
| Epitopes | Transcript Variant JNK1-A1 (5), C-Term (2), N-Term (2), pTyr185 (2), Center (1), pT183 (1), pThr183 (1), pThr183,pTyr185 (1), pY185 (1) |
