MMP-9 antibody
| Antigen |
|
| Clonality |
Monoclonal (2C3) |
|
Host
|
|
|
Reactivity
|
Human (71), Rat (Rattus) (20), Mouse (Murine) (19), Cow (Bovine) (10), Dog (Canine) (9), Horse (Equine) (9), Pig (Porcine) (9), Rabbit (8), Chicken (3), Guinea Pig (2), Sheep (Ovine) (2)
|
|
Application
|
Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Western Blotting (WB) (50), Immunoprecipitation (IP) (23), Immunofluorescence (IF) (22), Flow Cytometry (FACS) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (11), ELISA (9), Immunohistochemistry (IHC) (6), Enzyme Immunoassay (EIA) (3), Immunocytochemistry (ICC) (2), Immunoelectron Microscopy (IEM) (1)
|
| Catalog no. |
ABIN314046 |
| Quantity |
25 ug (Variants) |
| Price |
Product not available in this region.
|
| Shipping to |
|
|
Alternative name
|
MMP9
|
|
Immunogen
|
Ovalbumin-conjugated synthetic Peptide KLGLGADVAQVT
|
|
Format
|
Purified
|
|
Isotype
|
IgG1, kappa chain (Matching secondary antibodies)
|
|
Clone
|
2C3
|
|
Description
|
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within theextracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases,stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to becleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought toplay an important role in tissue remodeling associated with various physiological and pathological processes. MMP9degrades of proteins in the extracellular matrix and activates growth factors like proTGFb and proTNFa. MMP-9contributes to the invasion and metastasis of various human malignancies. Clone F11P2C3 has been shown to beuseful for western blotting and immunohistochemistry of human MMP9.
|
|
Application Notes
|
Each lot of this antibody is quality control tested by Western blotting. ForWestern blotting, suggested working dilution(s): Use 5-10 ug per 5 mlantibody dilution buffer for each mini-gel. It is recommended that the reagentbe titrated for optimal performance for each application.
|
|
Purification
|
This antibody was purified by affinity chromatography.
|
|
Buffer
|
This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide at 0.5 mg/ml.
|
|
Storage
|
Upon receipt, store undiluted at 4 degrees C.
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "MMP-9", type "Antibodies"
|
Hosts
|
Rabbit (43), Mouse (35), Sheep (3)
|
|
Reactivities
|
Human (71), Rat (Rattus) (20), Mouse (Murine) (19), Cow (Bovine) (10), Dog (Canine) (9), Horse (Equine) (9), Pig (Porcine) (9), Rabbit (8), Chicken (3), Guinea Pig (2), Sheep (Ovine) (2)
|
|
Applications
|
Western Blotting (WB) (50), Immunoprecipitation (IP) (23), Immunofluorescence (IF) (22), Flow Cytometry (FACS) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (11), ELISA (9), Immunohistochemistry (IHC) (6), Enzyme Immunoassay (EIA) (3), Immunocytochemistry (ICC) (2), Immunoelectron Microscopy (IEM) (1)
|
|
Conjugates
|
Biotin (4), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
|
|
Epitopes
|
C-Term (3), AA 659-674 (1), active (1)
|