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MMP-9 antibody

Antigen

MMP-9

Clonality Monoclonal (2C3)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Application
Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Catalog no. ABIN314046
Quantity 25 ug  (Variants)
Price Product not available in this region.
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Additional Information

Alternative name MMP9
Immunogen Ovalbumin-conjugated synthetic Peptide KLGLGADVAQVT
Format Purified
Isotype IgG1, kappa chain  (Matching secondary antibodies)
Clone 2C3
Description Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within theextracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases,stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to becleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought toplay an important role in tissue remodeling associated with various physiological and pathological processes. MMP9degrades of proteins in the extracellular matrix and activates growth factors like proTGFb and proTNFa. MMP-9contributes to the invasion and metastasis of various human malignancies. Clone F11P2C3 has been shown to beuseful for western blotting and immunohistochemistry of human MMP9.

Application Details

Application Notes Each lot of this antibody is quality control tested by Western blotting. ForWestern blotting, suggested working dilution(s): Use 5-10 ug per 5 mlantibody dilution buffer for each mini-gel. It is recommended that the reagentbe titrated for optimal performance for each application.
Purification This antibody was purified by affinity chromatography.
Buffer This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide at 0.5 mg/ml.
Storage Upon receipt, store undiluted at 4 degrees C.
Restrictions For Research Use only

Alternatives

Alternatives for antigen "MMP-9", type "Antibodies"
Hosts Rabbit (43), Mouse (35), Sheep (3)
Reactivities Human (71), Rat (Rattus) (20), Mouse (Murine) (19), Cow (Bovine) (10), Dog (Canine) (9), Horse (Equine) (9), Pig (Porcine) (9), Rabbit (8), Chicken (3), Guinea Pig (2), Sheep (Ovine) (2)
Applications Western Blotting (WB) (50), Immunoprecipitation (IP) (23), Immunofluorescence (IF) (22), Flow Cytometry (FACS) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (11), ELISA (9), Immunohistochemistry (IHC) (6), Enzyme Immunoassay (EIA) (3), Immunocytochemistry (ICC) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Biotin (4), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes C-Term (3), AA 659-674 (1), active (1)