RIG-1 antibody

Antigen: RIG-1

Clonality: Monoclonal (SS1A)

Host: Rat

Reactivity: Mouse (Murine)

Application: Western Blotting (WB)

Catalog no.: ABIN314101

Additional Information

Immunogen: Peptide-KLH, C-terminal end of murine RIG-1

Format: Purified

Isotype: IgG2a, kappa chain  (Matching secondary antibodies)

Clone: SS1A

Description: RIG-1/DDX58(Retinoic acid-inducible gene 1 protein/ DEAD-box protein 58)is an RNA helicase that belongs to the DEAD/H box. Contains 2 CARDdomains, a helicase ATP-binding domain and a helicase C-terminal domain.Predicted molecular weight approximately 107 kD. RIG-1 has an essentialfunction in double-stranded RNA-induced innate antiviral responses. RIG-1and MDA5 (melanoma differentiation-associated gene 5) are key intracellularreceptors that sense intracellular viral infection and trigger a signal for innateantiviral responses including the production of type I IFN. Clone SS1A hasbeen shown to be useful for western blotting of the mouse RIG-1 protein.

Application Details

Purification: This antibody was purified by affinity chromatography.

Buffer: This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide at 0.5 mg/ml.

Storage: Upon receipt, store undiluted at 4 degrees C.

Restrictions: For Research Use only