CD247 Molecule (CD247) antibody

Antigen: CD247 Molecule (CD247)

Synonyms: T3Z, CD3H, CD3Q, CD3Z, TCRZ, CD3-ZETA, Cd3, T3z, Cd3h, Cd3z, TCRk, Tcrz, CD3-eta, CD3zeta, AW552088, CD3-zeta, 4930549J05Rik, A430104F18Rik, CD247, im:7156386, LOC100136514, LOC100136549, LOC100305023

Clonality: Monoclonal (6B10-2)

Host: Mouse

Reactivity: Human, Mouse (Murine)

Application: Western Blotting (WB), Intracellular Flow Cytometry (ICFC)

Catalog no.: ABIN314134

Additional Information

Alternative name: TCR zeta chain (CD247)

Immunogen: Human TCR zeta chain aa38-54

Format: Purified

Isotype: IgG1, kappa chain  (Matching secondary antibodies)

Clone: 6B10-2

Description: The invariant TCR zeta chain is a member of the CD3 complex associated with the clonotypic alpha/beta TCRhetrodimer. The disulfide-linked TCRzeta homodimers transmit signals following TCR ligation. Loss of TCR zetaexpression has been reported in a diverse range of disease states, including autoimmune diseases, many neoplastic conditions and chronic infections, such as tuberculosis and leprosy.

Application Details

Application Notes: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s):Use 0.5-1 μg per ml antibody dilution buffer. It is recommended that the reagent be titrated for optimal performancefor each application. 1.Zhang Z et al. 2007. 109:43282.Gorman CL et al. 2008. J Immunol 180:10603.Jenson WA et al. 1997. Eur J Immunol 27:707

Purification: The antibody was purified by affinity chromatography.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Storage: The antibody solution should be stored undiluted at 4 degrees C.

Restrictions: For Research Use only