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Antibodies
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anti-TIMP Metallopeptidase Inhibitor 2 (TIMP2) antibody
TIMP Metallopeptidase Inhibitor 2 (TIMP2) antibody
| Antigen |
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| Synonyms |
CSC-21K, MGC84288, MGC108274, TIMP-2, TIMP2, timp2 |
| Clonality |
Monoclonal (F27P3A4) |
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Host
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Reactivity
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 Alternatives Human, Mouse (Murine), Rabbit, Chicken, Zebrafish (Danio rerio), Pig (Porcine)
Human (91), Mouse (Murine) (32), Rat (Rattus) (28), Rabbit (24), Cow (Bovine) (21), Pig (Porcine) (21), Guinea Pig (5), Chicken (4), Dog (Canine) (2), Monkey (2), Zebrafish (Danio rerio) (2)
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Application
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Alternatives Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
Western Blotting (WB) (73), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (41), Immunofluorescence (IF) (36), Flow Cytometry (FACS) (23), ELISA (17), Immunoprecipitation (IP) (17), Enzyme Immunoassay (EIA) (13), Immunohistochemistry (Frozen Sections) (IHC (fro)) (10), Immunohistochemistry (IHC) (5), ELISA (Detection) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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| Catalog no. |
ABIN314145 |
| Quantity |
25 ug (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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TIMP-2
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Immunogen
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Ovalbumin-conjugated synthetic Peptide DSGNDIYGNPI
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Format
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Purified
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Isotype
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IgG2a, kappa chain (Matching secondary antibodies)
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Clone
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F27P3A4
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Description
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TIMP-2 (Tissue inhibitor of metalloproteinase 2) is a nonglycosylated protein that belongs to the protease inhibitor I35(TIMP) family. Contains 1 NTR domain, predicted molecular weight 24 kD. The mechanisms of TIMPs inhibitangiogenesis appear to be specific for each member of the TIMP family. TIMP-2 binds to the surface of humanendothelial cells through interaction with the integrin alpha3beta1, and abrogates angiogenic factor induced endothelial cellproliferation in vitro and angiogenesis in vivo independent of MMP inhibition. Clone F27P3A4 has been shown to beuseful for western blotting, immunohistochemistry and ELISA of human, mouse, rabbit, chicken, zebrafish, and pigTIMP-2.
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Application Notes
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Each lot of this antibody is quality control tested by Western blotting. ForWestern blotting, suggested working dilution(s): Use 5-10 ug per 5 mlantibody dilution buffer for each mini-gel. It is recommended that the reagentbe titrated for optimal performance for each application.
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Purification
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This antibody was purified by affinity chromatography.
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Buffer
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This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide at 0.5 mg/ml.
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Storage
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Upon receipt, store undiluted at 4 degrees C.
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Restrictions
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For Research Use only
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Alternatives for antigen "TIMP Metallopeptidase Inhibitor 2 (TIMP2)", type "Antibodies"
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Hosts
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Mouse (54), Rabbit (41), Sheep (3), Goat (2)
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Reactivities
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Human (91), Mouse (Murine) (32), Rat (Rattus) (28), Rabbit (24), Cow (Bovine) (21), Pig (Porcine) (21), Guinea Pig (5), Chicken (4), Dog (Canine) (2), Monkey (2), Zebrafish (Danio rerio) (2)
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Applications
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Western Blotting (WB) (73), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (41), Immunofluorescence (IF) (36), Flow Cytometry (FACS) (23), ELISA (17), Immunoprecipitation (IP) (17), Enzyme Immunoassay (EIA) (13), Immunohistochemistry (Frozen Sections) (IHC (fro)) (10), Immunohistochemistry (IHC) (5), ELISA (Detection) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Biotin (7), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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N-Term (2)
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