SLC7A11 antibody (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11) (N-Term) (Biotin)

Details for Product anti-SLC7A11 Antibody No. ABIN314185, Supplier: Log in to see
Antigen
  • SLC7A11
  • DKFZp468E122
  • CCBR1
  • xCT
  • 9930009M05Rik
  • AI451155
  • sut
  • solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
  • solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
  • SLC7A11
  • Slc7a11
Epitope
N-Term, AA 1-50
49
32
15
14
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
88
36
36
3
3
2
2
1
1
1
1
1
1
1
1
1
Host
Rabbit
74
19
Clonality
Polyclonal
Conjugate
This SLC7A11 antibody is conjugated to Biotin
6
5
4
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
62
31
22
22
20
16
13
9
1
Options
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Immunogen A synthetic peptide made to an N-terminal region of the human xCT protein (between residues 1-50) [UniProt Q9UPY5].
Purification Immunogen affinity purified
Alternative Name xCT (SLC7A11 Antibody Abstract)
Background Gene Symbol: SLC7A11
Molecular Weight Theoretical MW: 57 kDa
Gene ID 23657
UniProt Q9UPY5
Application Notes Western Blot 1:1000, Immunohistochemistry 5 μg/mL, Immunohistochemistry-Paraffin 5 μg/mLThis xCT antibody is useful for Western blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry and Flow (PMID 20028852). Immunoprecipitation is not recommended. In Western blot this antibody recognizes a band at ~55 kDa, and in ICC/IF membrane staining was observed in HepG2 cells. Permeablization is recommended prior to performing Flow analysis. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer PBS
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C in the dark.
Product cited in: Liu, Blower, Pham, Fang, Dai, Wise, Green, Teitel, Ning, Ling, Lyn-Cook, Kadlubar, Sadée, Huang: "Cystine-glutamate transporter SLC7A11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin." in: Molecular pharmacology, Vol. 72, Issue 6, pp. 1637-46, 2007 (PubMed).

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