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Antibodies
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anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (N-Term) antibody
Chemokine (C-C Motif) Receptor 6 (CCR6) (N-Term) antibody
| Antigen |
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| Synonyms |
BN-1, CKR6, DCR2, CD196, CKRL3, DRY-6, GPR29, CKR-L3, CMKBR6, GPRCY4, STRL22, GPR-CY4, CCR-6, KY411, Cmkbr6, CC-CKR-6, MGC108876, CCR6 |
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Epitope
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| Clonality |
Monoclonal (4C6) |
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Host
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Reactivity
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Application
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 Alternatives Enzyme Immunoassay (EIA), Western Blotting (WB)
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| Catalog no. |
ABIN316598 |
| Quantity |
50 µl (1.0 mg/ml) (Variants) |
| Price |
265.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: C-C chemokine receptor type 6, C-C CKR-6, CC-CKR-6, CCR-6, CKRL3, CMKBR6, GPR29,STRL22, DRY6, GPR-CY4, LARC receptor, G-protein coupled receptor 29, Chemokinereceptor-like 3
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Alternative name
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CD196 / CCR6
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Swiss-Prot
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P51684
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Immunogen
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Recombinant human CCR6 (1-46aa)
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Cross-Reactivity
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Human
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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4C6
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Description
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CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seventransmembrane protein similar to G protein-coupled receptors. The gene is preferentiallyexpressed by immature dendritic cells and memory T cells. The ligand of this receptor ismacrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown tobe important for B-lineage maturation and antigen-driven B-cell differentiation, and it mayregulate the migration and recruitment of dentritic and T cells during inflammatory andimmunological responses. CCR6 has been reported to be expressed in intestine, colon,liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It hasalso been reported to be expressed in lymphocytes, T cells, and B cells.
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Specificity
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This antibody detects human CCR6. Other species not tested.
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Application Notes
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ELISA. Western blot (1: 500 - 1: 1,000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1.0 mg/ml
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Purification
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Purified
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Buffer
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PBS, pH 7.4, containing 0.09 % Sodium Azide
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Storage
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Store the antibody at 2-8°C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Restrictions
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For Research Use only
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Alternatives for antigen "Chemokine (C-C Motif) Receptor 6 (CCR6)", type "Antibodies"
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Hosts
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Rabbit (7), Mouse (4)
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Reactivities
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Human (10), Mouse (Murine) (2), Monkey (1), Rat (Rattus) (1)
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Applications
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Western Blotting (WB) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Enzyme Immunoassay (EIA) (3), Flow Cytometry (FACS) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoprecipitation (IP) (2), ELISA (Detection) (1)
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Epitopes
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AA 18-46 (1), N-Term (1)
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