LTBR antibody (Extracellular Domain)

Catalog No. ABIN317398

Product Details anti-LTBR Antibody

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Binding Specificity: Extracellular Domain

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This LTBR antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Characteristics: Synonyms: Tumor necrosis factor receptor 3, TNF-R3, Tumor necrosis factor C receptor, TNFCR,TNFRSF3, D12S370, Lymphotoxin-beta receptor, Tumor necrosis factor receptor superfamilymember 3, Tumor necrosis factor receptor type III, Tumor necrosis factor receptor 2-relatedprotein

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Endotoxin Level: Low Endotoxin

Immunogen: Recombinant extracellular domain of LT beta R

Clone: 5G11b

Isotype: IgG2a

Application Details

Application Notes: Flow cytometry: 1/50 - 1/100. Functional assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline pH 7.4, azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for LTBR

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Alternative Name: LTBR / TNFR3 (LTBR Products)

Synonyms: AI256028 antibody, CD18 antibody, LTbetaR antibody, Ltar antibody, TNF-R-III antibody, TNFCR antibody, TNFR-RP antibody, TNFR2-RP antibody, TNFRrp antibody, Tnfbr antibody, Tnfrsf3 antibody, D12S370 antibody, LT-BETA-R antibody, TNFR3 antibody, TNFRSF3 antibody, lymphotoxin beta receptor antibody, lymphotoxin B receptor antibody, Ltbr antibody, LTBR antibody

Background: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin alpha and lymphtoxin beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.Synonyms: D12S370, Lymphotoxin-beta receptor, TNF-R3, TNFCR, TNFRSF3, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor 3, Tumor necrosis factor receptor superfamily member 3, Tumor necrosis factor receptor type III

UniProt: P50284

Pathways: NF-kappaB Signaling