Integrin beta 3 antibody (ITGB3) (FITC)

Details for Product anti-ITGB3 Antibody No. ABIN317409, Supplier: Log in to see
Antigen
  • CD61
  • GP3A
  • INGRB3
  • BDPLT16
  • BDPLT2
  • GPIIIa
  • GT
  • INTB3
  • integrin
  • GPIIIA
  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • integrin beta 3
  • integrin, beta 3
  • ITGB3
  • Itgb3
Alternatives
anti-Cow (Bovine) Integrin beta 3 antibody for Immunofluorescence (fixed cells)
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Pig (Porcine)
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Host
Mouse
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Clonality (Clone)
Monoclonal ()
Conjugate
This Integrin beta 3 antibody is conjugated to FITC
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Application
Flow Cytometry (FACS)
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Options
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Immunogen Porcine peripheral blood mononuclear cells
Clone JM2E5
Isotype IgG1
Characteristics Synonyms: Integrin beta-3, GP3A, GPIIIa, Platelet membrane glycoprotein IIIa
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Alternative Name CD61 / ITGB3 (ITGB3 Antibody Abstract)
Background CD61 is expressed by platelets and megakaryocytes, but not by other haematopoietic cells.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
UniProt P05106
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
Application Notes Flow Cytometry: use 10 μL of neat antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % Bovine Serum Albumin as stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C for up to one month or at -20 °C for longer. Avoid repeatedfreezing and thawing. This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-Integrin beta 3 antibody (ITGB3)  (FITC) (ABIN317409) anti-Integrin beta 3 (ITGB3) antibody (FITC)
Background publications Merono, Lucena, López, Garrido, Pérez, Llanes: "Immunohistochemical analysis of beta3 integrin (CD61): expression in pig tissues and human tumors." in: Histology and histopathology, Vol. 17, Issue 2, pp. 347-52, 2002 (PubMed).

Arce, Moreno, Pérez de la Lastra, Garrido, Barbancho, De Andrés, Morera, Llanes: "Expression of CD61 (beta3 integrin subunit) on canine cells." in: Platelets, Vol. 12, Issue 2, pp. 69-73, 2001 (PubMed).

Pérez de la Lastra, Moreno, Pérez, Llanes: "Characterization of the porcine homologue to human platelet glycoprotein IIb-IIIa (CD41/CD61) by a monoclonal antibody." in: Tissue antigens, Vol. 49, Issue 6, pp. 588-94, 1997 (PubMed).