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CD1d antibody (CD1d Molecule)

Details for Product anti-CD1D Antibody No. ABIN317451, Supplier: Login to see New
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Synonyms CD1D, CD1.1, CD1.2, CD1D1, CD1A, R3, AI747460, Cd1a, Cd1d, Ly-38, Cd1
(103), (63), (47)
(90), (62), (41)
Clonality (Clone)
Monoclonal ()
This CD1d antibody is un-conjugated
(21), (17), (15), (7), (4), (2), (2), (2), (2), (2), (2), (1), (1)
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(99), (88), (52), (49), (35), (33), (21), (20), (12), (8), (6), (5), (5), (2), (1), (1), (1)
Pubmed 6 references available
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Quantity 0.2 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Beta G2 - CD1d fusion protein
Clone NOR3-2
Isotype IgG1
Specificity This antibody recognizes the CD1d gene product, a 49 kDa heavy chain associated with Beta 2 microglobulin on cortical thymocytes. Beta 2 microglobulin independent expression of CD1d has also been demonstrated on human intestinal epithelial cells.
Characteristics Synonyms: R3G1, T-cell surface glycoprotein CD1d
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Alternative Name CD1d (CD1D Antibody Abstract)
Background CD1c is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin.CD1c is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail.Synonyms: R3G1, T-cell surface glycoprotein CD1d
Gene ID 912
UniProt P15813
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Immunohistochemistry on frozen sections. Immunoprecipitation. Does not work on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline 0.09 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C forlonger. Avoid repeated freezing and thawing. Should this product contain a precipitate werecommend microcentrifugation before use.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-CD1d antibody (CD1d Molecule) (ABIN317451) anti-CD1d Molecule (CD1D) antibody
Background publications Zeissig, Dougan, Barral et al.: "Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function. ..." in: The Journal of clinical investigation, Vol. 120, Issue 8, pp. 2889-99, 2010 (PubMed).

Moll, Andersson, Smed-Sörensen et al.: "Inhibition of lipid antigen presentation in dendritic cells by HIV-1 Vpu interference with CD1d recycling from endosomal compartments." in: Blood, Vol. 116, Issue 11, pp. 1876-84, 2010 (PubMed).

Spanoudakis, Hu, Naresh et al.: "Regulation of multiple myeloma survival and progression by CD1d." in: Blood, Vol. 113, Issue 11, pp. 2498-507, 2009 (PubMed).

Im, Tapinos, Chae et al.: "Expression of CD1d molecules by human schwann cells and potential interactions with immunoregulatory invariant NK T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 8, pp. 5226-35, 2006 (PubMed).

Agea, Russano, Bistoni et al.: "Human CD1-restricted T cell recognition of lipids from pollens." in: The Journal of experimental medicine, Vol. 202, Issue 2, pp. 295-308, 2005 (PubMed).

Bonish, Jullien, Dutronc et al.: "Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependent IFN-gamma production by NK-T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 7, pp. 4076-85, 2000 (PubMed).

Catalog No. ABIN317451
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