PPM1G antibody (AA 317-546)

Catalog No. ABIN317552

Product Details anti-PPM1G Antibody

Target: PPM1G (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G))

Binding Specificity: AA 317-546

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPM1G antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: The antibody recognizes human PPM1G. Other species not tested.

Characteristics: Synonyms: Protein phosphatase 2C isoform gamma, Protein phosphatase 1C, PPM1C, PP2C-gamma,Protein phosphatase magnesium-dependent 1 gamma

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human PPM1G (317-546 aa) purified from E. coli

Clone: K1G6

Isotype: IgG1

Application Details

Application Notes: ELISA. Western blot (1: 1,000 - 1: 2,000). Immunohistochemistry on paraffin sections (1: 50 - 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 10 % glycerol and 0.01 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for PPM1G

Target: PPM1G (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G))

Alternative Name: Protein Phosphatase 1G / PPM1G (PPM1G Products)

Synonyms: AI385652 antibody, Fin13 antibody, PP2CG antibody, PP2CGAMMA antibody, PPP2CG antibody, protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform antibody, protein phosphatase, Mg2+/Mn2+ dependent 1G antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1G antibody, Ppm1g antibody, PPM1G antibody

Background: PPM1G (Protein phosphatase 1G) is a member of the PP2C family of Serine/threonine protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The human Ser/Thr phosphatase PPM1G promotes spliceosome assembly. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome.Synonyms: PP2C-gamma, PPM1C, Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, Protein phosphatase magnesium-dependent 1 gamma

Gene ID: 5496

UniProt: O15355