TAS2R1 antibody

Catalog No. ABIN317775

Product Details anti-TAS2R1 Antibody

Target: TAS2R1 (Taste Receptor, Type 2, Member 1 (TAS2R1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAS2R1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: T2R1 antibody detects endogenous levels of T2R1 protein.(region surrounding Asp45)

Purification: Affinity chromatography

Application Details

Application Notes: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TAS2R1

Target: TAS2R1 (Taste Receptor, Type 2, Member 1 (TAS2R1))

Alternative Name: TAS2R1 (TAS2R1 Products)

Synonyms: T2R1 antibody, TRB7 antibody, taste 2 receptor member 1 antibody, TAS2R1 antibody

Background: The sense of taste is essential for the survival of organisms. For example, the ability to identify sweet-tasting foods enables animals to seek out food with high nutritive value, whereas the ability to identify bitter substances enables them to avoid the ingestion of potentially harmful substances. A family of integral membrane proteins are involved in taste perception and include T1R, which is involved in sweet taste perception and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. Specifically, T2R1 is expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.Synonyms: TRB7, Taste receptor T2R1, Taste receptor family B member 7, Taste receptor type 2 member 1

Molecular Weight: approx. 33 kDa

Gene ID: 50834

NCBI Accession: NP_062545

UniProt: Q9NYW7